Incidence and seasonality of type 1 diabetes: a population-based 3-year cohort study using the National Database in Japan.
Incidence and seasonality of type 1 diabetes: a population-based 3-year cohort study using the National Database in Japan.
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DOI：
10.1136/bmjdrc-2020-001262
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发表时间：
2020-09
影响因子：
4.1
通讯作者：
Imamura T
中科院分区：
文献类型：
--
作者：
Nishioka Y;Noda T;Okada S;Myojin T;Kubo S;Higashino T;Ishii H;Imamura T
调查日本各年龄组（0-19岁、20-39岁、40-59岁、≥60岁）1型糖尿病的发病率及其是否存在季节性。2014年9月至2017年8月，日本国家健康保险索赔和特定健康检查数据库的2013-2018年数据估计了1型糖尿病的发病率。采用Tango指数和自控病例序列法对发病率进行分析。总的来说，在79 175 553名纳入的个体中，有10 400人被诊断为1型糖尿病。2014年9月至2017年8月1型糖尿病发病率为4.42/10万人年。0-19岁、20-39岁、40-59岁和≥60岁男性的发病率分别为3.94、5.57、5.70和3.48。在女性中，同一年龄段的发病率分别为5.22、4.83、4.99和3.31。Tango指数显示0-19岁人群1型糖尿病发病率与季节有显著相关性。此外，自我对照病例系列方法显示年龄和季节之间存在显著的相互作用，20岁以下患者的1型糖尿病发病率在春季较高。在日本，40-59岁的男性和0-19岁的女性是1型糖尿病发病率最高的人群。此外，日本年轻发病糖尿病的发病率在春季（3 - 5月）较高。
To investigate the incidence of type 1 diabetes by age group (0–19, 20–39, 40–59, ≥60 years) in Japan and whether there is seasonality in this incidence. The incidence of type 1 diabetes from September 2014 to August 2017 was estimated using 2013–2018 data from the National Database of Health Insurance Claims and Specific Health Check-ups of Japan. The incidence rate was analyzed using Tango’s Index and the self-controlled case series method. Overall, 10 400 of the 79 175 553 included individuals were diagnosed with type 1 diabetes. The incidence of type 1 diabetes from September 2014 to August 2017 was 4.42/100 000 person-years. The incidence rates for men aged 0–19, 20–39, 40–59, and ≥60 years were 3.94, 5.57, 5.70, and 3.48, respectively. Among women, the incidence rates for the same age ranges were 5.22, 4.83, 4.99, and 3.31, respectively. Tango’s index showed that the incidence rate of type 1 diabetes was significantly associated with seasons among those aged 0–19 years. Further, the self-controlled case series method showed a significant interaction between age and season, with the incidence of type 1 diabetes being higher in spring for patients younger than 20 years of age. In Japan, men aged 40–59 years and women aged 0–19 years are the groups with the highest incidence of type 1 diabetes. Further, the incidence of younger-onset diabetes in Japan was higher in spring (from March to May).
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DOI：
10.1016/s2213-8587(17)30362-5
发表时间：
2018-03
期刊：
The lancet. Diabetes & endocrinology
影响因子：
--
作者：
Thomas NJ;Jones SE;Weedon MN;Shields BM;Oram RA;Hattersley AT
通讯作者：
Hattersley AT
影响因子：
3.4
作者：
Mayer-Davis, Elizabeth J.;Kahkoska, Anna R.;Craig, Maria E.
通讯作者：
Craig, Maria E.
影响因子：
16.2
作者：
Shamis, I;Gordon, O;Laron, Z
通讯作者：
Laron, Z
影响因子：
3.8
作者：
Mamoulakis, D;Galanakis, E;Sbyrakis, S
通讯作者：
Sbyrakis, S
影响因子：
2.6
作者：
Schroeder EB;Donahoo WT;Goodrich GK;Raebel MA
通讯作者：
Raebel MA