Necrotizing enterocolitis: current understanding of the prevention and management.

Necrotizing enterocolitis: current understanding of the prevention and management.
复制标题

DOI:
10.1007/s00383-023-05619-3
复制
发表时间:
2024-01-10
影响因子:
1.8
通讯作者:
Xu, Yunyun
Xu, Yunyun
中科院分区:
医学3区
文献类型:
--
作者:
Hu, Xiaohan;Liang, Hansi;Li, Fang;Zhang, Rui;Zhu, Yanbo;Zhu, Xueping;Xu, Yunyun

文献摘要

参考文献

相似文献

坏死性小肠结肠炎(NEC)是新生儿疾病之一,发病率和死亡率较高,尤其是早产儿。本文旨在简要介绍NEC的最新流行病学、易感因素以及临床诊断和表现。我们还根据不同的发病机制,按危险因素组织了新的预防策略,然后根据Bell分期和并发症,以及根据临床和影像学表现的轻度到重度分类,讨论了新的治疗方法。这样的概括将有助于临床医生和研究人员对该疾病有更深入的了解,并进行更有针对性的分类、分级预防和探索。我们专注于 NEC 早期和疑似阶段的预防和治疗,包括发现新的生物标志物和控制疾病进展的药物。同时讨论了其临床应用、未来发展以及不足之处。
Necrotizing enterocolitis (NEC) is one of the diseases in neonates, with a high morbidity and mortality rate, especially in preterm infants. This review aimed to briefly introduce the latest epidemiology, susceptibility factors, and clinical diagnosis and presentation of NEC. We also organized new prevention strategies by risk factors according to different pathogeneses and then discussed new treatment methods based on Bell's staging and complications, and the classification of mild to high severity based on clinical and imaging manifestations. Such a generalization will help clinicians and researchers to gain a deeper understanding of the disease and to conduct more targeted classification, grading prevention, and exploration. We focused on prevention and treatment of the early and suspected stages of NEC, including the discovery of novel biomarkers and drugs to control disease progression. At the same time, we discussed its clinical application, future development, and shortcomings.
DOI: 10.1038/s41390-020-01125-7
发表时间: 2021-05
期刊: Pediatric research
影响因子: 3.6
作者:
Knowles TA;Hosfield BD;Pecoraro AR;Li H;Shelley WC;Markel TA
通讯作者: Markel TA
代谢组学和蛋白质组学时代用于预测和早期诊断坏死性小肠结肠炎的新兴生物标志物。
DOI: 10.3389/fped.2020.602255
发表时间: 2020
影响因子: 2.6
作者:
Agakidou E;Agakidis C;Gika H;Sarafidis K
通讯作者: Sarafidis K
DOI: 10.1007/s00330-018-5362-x
发表时间: 2018-09
期刊: European radiology
影响因子: 5.9
作者:
Ahle M;Ringertz HG;Rubesova E
通讯作者: Rubesova E
DOI: 10.1038/labinvest.2011.167
发表时间: 2012-03
期刊: Laboratory investigation; a journal of technical methods and pathology
影响因子: --
作者:
通讯作者: --
DOI: 10.1016/j.amjsurg.2015.08.004
发表时间: 2015-12-01
影响因子: 3
作者:
Akinkuotu, Adesola C.;Nuthakki, Sushma;Olutoye, Oluyinka O.
通讯作者: Olutoye, Oluyinka O.