Optical coherence tomography (OCT) reveals depth-resolved dynamics during functional brain activation.
Optical coherence tomography (OCT) reveals depth-resolved dynamics during functional brain activation.
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DOI:
10.1016/j.jneumeth.2008.11.026
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发表时间:
2009-03-30
影响因子:
3
通讯作者:
Fujimoto, James G.
中科院分区:
文献类型:
--
作者:
Chen, Yu;Aguirre, Aaron D.;Ruvinskaya, Lana;Devor, Anna;Boas, David A.;Fujimoto, James G.
关键词:
Optical intrinsic signal imaging (OISI) provides two-dimensional, depth-integrated activation maps of brain activity. Optical coherence tomography (OCT) provides depth-resolved, cross-sectional images of functional brain activation. Co-registered OCT and OISI imaging was performed simultaneously on the rat somatosensory cortex through a thinned skull during forepaw electrical stimulation. Fractional signal change measurements made by OCT revealed a functional signal that correlates well with that of the intrinsic hemodynamic signals and provides depth-resolved, layer-specific dynamics in the functional activation patterns indicating retrograde vessel dilation. OCT is a promising a new technology which provides complementary information to OISI for functional neuroimaging.
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DOI:
10.1073/pnas.94.26.14826
发表时间:
1997-12-23
影响因子:
11.1
作者:
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DOI:
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1998-12-22
影响因子:
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Denk, W
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