Evaluation of left ventricular ejection fraction using through-time radial GRAPPA.
Evaluation of left ventricular ejection fraction using through-time radial GRAPPA.
复制标题
DOI：
10.1186/s12968-014-0079-8
复制
发表时间：
2014-10-01
期刊：
影响因子：
--
通讯作者：
Seiberlich N
中科院分区：
文献类型：
--
作者：
Aandal G;Nadig V;Yeh V;Rajiah P;Jenkins T;Sattar A;Griswold M;Gulani V;Gilkeson RC;Seiberlich N
使用心血管磁共振 (CMR) 测定左心室射血分数需要稳定的心律以进行心电图 (ECG) 门控和多次屏气以尽量减少呼吸运动伪影，这通常会导致扫描时间长达几分钟。通过采用实时 CMR 方法（例如实时径向 GRAPPA）可以消除对门控和屏气的需要。本研究的目的是将使用当前金标准屏气心电图门控功能扫描与使用径向 GRAPPA 的非门控自由呼吸实时成像获得的左心室心脏功能参数进行比较，并确定使用这种实时方法时是否会减少扫描时间或伪影的发生。使用门控和屏气的标准心功能检查以及实时方法对 63 名患者进行了 1.5T CMR 扫描仪扫描。记录总扫描持续时间。采用实时径向 GRAPPA 从高度加速的实时数据重建图像。评估左心室的血容量以确定两种方法的收缩末期容积 (ESV)、舒张末期容积 (EDV) 和射血分数 (EF)，并由两名心脏读数器对图像中是否存在伪影和特定图像特征的质量进行评级。进行线性回归分析、Bland-Altman 图和双边 t 检验来比较定量参数。进行双样本 t 检验来比较扫描持续时间，并使用双样本比例检验来分析伪影的存在。对于审稿人的评分，采用了Wilcoxon 测试来衡量分数分布的平等性。金标准方法和实时方法之间的 EF、EDV 和 ESV 差异不具有统计显着性（p 值分别为 0.77、0.82 和 0.97）。此外，实时数据收集的扫描时间显着缩短 (p<0.001)，并且实时图像中报告的伪影更少 (p<0.01)。在定性图像分析中，评审者稍微喜欢标准图像，尽管包括心脏运动在内的一些特征具有相同的评级。在自由呼吸下无需 ECG 门控的实时功能 CMR 与实时径向 GRAPPA 可以被视为评估患者射血分数的金标准屏气电影成像的替代方案。
The determination of left ventricular ejection fraction using cardiovascular magnetic resonance (CMR) requires a steady cardiac rhythm for electrocardiogram (ECG) gating and multiple breathholds to minimize respiratory motion artifacts, which often leads to scan times of several minutes. The need for gating and breathholding can be eliminated by employing real-time CMR methods such as through-time radial GRAPPA. The aim of this study is to compare left ventricular cardiac functional parameters obtained using current gold-standard breathhold ECG-gated functional scans with non-gated free-breathing real-time imaging using radial GRAPPA, and to determine whether scan time or the occurrence of artifacts are reduced when using this real-time approach. 63 patients were scanned on a 1.5T CMR scanner using both the standard cardiac functional examination with gating and breathholding and the real-time method. Total scan durations were noted. Through-time radial GRAPPA was employed to reconstruct images from the highly accelerated real-time data. The blood volume in the left ventricle was assessed to determine the end systolic volume (ESV), end diastolic volume (EDV), and ejection fraction (EF) for both methods, and images were rated for the presence of artifacts and quality of specific image features by two cardiac readers. Linear regression analysis, Bland-Altman plots and two-sided t-tests were performed to compare the quantitative parameters. A two-sample t-test was performed to compare the scan durations, and a two-sample test of proportion was used to analyze the presence of artifacts. For the reviewers´ ratings the Wilcoxon test for the equality of the scores’ distributions was employed. The differences in EF, EDV, and ESV between the gold-standard and real-time methods were not statistically significant (p-values of 0.77, 0.82, and 0.97, respectively). Additionally, the scan time was significantly shorter for the real-time data collection (p<0.001) and fewer artifacts were reported in the real-time images (p<0.01). In the qualitative image analysis, reviewers marginally preferred the standard images although some features including cardiac motion were equivalently rated. Real-time functional CMR with through-time radial GRAPPA performed without ECG-gating under free-breathing can be considered as an alternative to gold-standard breathhold cine imaging for the evaluation of ejection fraction in patients.
登录
查看更多内容
DOI：
10.1109/iembs.2009.5333482
发表时间：
2009
期刊：
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
影响因子：
--
作者：
Brinegar C;Zhang H;Wu YJ;Foley LM;Hitchens T;Ye Q;Pocci D;Lam F;Ho C;Liang ZP
通讯作者：
Liang ZP
DOI：
10.1016/s0735-1097(83)80278-2
发表时间：
1983-01-01
影响因子：
24
作者：
GORDON, EP;SCHNITTGER, I;POPP, RL
通讯作者：
POPP, RL
影响因子：
3.3
作者：
Feng, Li;Srichai, Monvadi B.;Lim, Ruth P.;Harrison, Alexis;King, Wilson;Adluru, Ganesh;Dibella, Edward V. R.;Sodickson, Daniel K.;Otazo, Ricardo;Kim, Daniel
通讯作者：
Kim, Daniel
DOI：
10.1186/1532-429x-15-79
发表时间：
2013-09-12
期刊：
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
影响因子：
--
作者：
Voit D;Zhang S;Unterberg-Buchwald C;Sohns JM;Lotz J;Frahm J
通讯作者：
Frahm J
影响因子：
24
作者：
Malm, S;Frigstad, S;Skjaerpe, T
通讯作者：
Skjaerpe, T