Impact of Coronavirus Disease 2019 on the Pediatric Population with Aerodigestive Disease.
Impact of Coronavirus Disease 2019 on the Pediatric Population with Aerodigestive Disease.
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DOI：
10.1016/j.jpeds.2021.12.022
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发表时间：
2022-04
期刊：
影响因子：
--
通讯作者：
Rosen R
中科院分区：
文献类型：
--
作者：
Beinvogl B;Cohen A;DiFilippo C;Kane M;Nurko S;Rosen R
确定2019冠状病毒病（COVID-19）隔离对呼吸消化系统疾病儿科患者的基线健康、药物使用、健康焦虑和医疗保健使用的影响，并评估常用处方药与COVID-19疾病风险的相关性。对2020年7月至2021年3月期间亲自到儿科神经胃肠病诊所就诊的患者进行的前瞻性研究。在招募的202名患者中，71.3%在呼吸消化疾病中心就诊，28.7%在功能性腹痛（FAP）/运动性门诊就诊。在所有患者中，25.1%的患者报告在隔离期间整体健康状况有所改善;与FAP/动力障碍患者（3.6%，P = .0001）相比，呼吸消化系统疾病患者（35.3%）报告整体健康状况改善的比例更高。呼吸消化系统疾病患者在隔离期间的气道症状较少（P <0.05），药物使用较少（吸入性类固醇，P <0.05和沙丁胺醇，P <0.05）。尽管客观上有所改善，但仍存在显著的健康相关焦虑，在隔离期间和隔离结束时报告的焦虑评分更高（P <0.05），患者组之间无差异（P > 0.11）。患者在隔离期间继续获得医疗保健。总的来说，28.7%的患者在急诊科就诊（FAP患者多于呼吸消化系统疾病患者，P = 0.02），19.8%的患者住院。在58.4%的患者中进行了COVID-19检测，整个队列中有2.0%（n = 4）检测呈阳性。在大流行期间，呼吸消化系统疾病患者的气道症状得到改善，药物使用减少，尽管与健康有关的焦虑增加。尽管由于广泛封锁而导致获得医疗服务的复杂性，但所有患者群体继续获得医疗服务。
To determine the impact of the coronavirus disease 2019 (COVID-19) quarantine on baseline health, medication use, health anxiety, and healthcare use in pediatric patients with aerodigestive disease and to evaluate for associations of commonly prescribed medications with the risk of COVID-19 illness. Prospective study of patients presenting in person to pediatric neurogastroenterology clinics between July 2020 and March 2021. Of 202 recruited patients, 71.3% were seen in the aerodigestive diseases center and 28.7% in the functional abdominal pain (FAP)/motility clinic. Of all patients, 25.1% reported improved overall health during quarantine; patients with aerodigestive disease (35.3%) reported higher rates of improved overall health compared with patients with FAP/motility disorders (3.6%, P = .0001). Patients with aerodigestive disease had fewer airway symptoms (P < .05) and less medication use during quarantine (inhaled steroids, P < .05 and albuterol, P < .05). Despite objective improvement, there was significant health-related anxiety, with greater anxiety scores reported during and at the end of quarantine (P < .05), with no difference between patient groups (P > .11). Patients continued to access healthcare during quarantine. In total, 28.7% of patients were seen in the emergency department (patients with FAP more than patients with aerodigestive disease, P = .02), and 19.8% were hospitalized. COVID-19 testing was performed in 58.4% of patients and 2.0% (n = 4) of the entire cohort tested positive. Patients with aerodigestive disease show improvement of airway symptoms and decreased use of medications during the pandemic, despite increased health-related anxiety. Despite complexities of accessing care due to the widespread lockdown, all patient groups continued to access healthcare.
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