Risk factors associated with clinical malaria episodes in Bangladesh: a longitudinal study.

Risk factors associated with clinical malaria episodes in Bangladesh: a longitudinal study.
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DOI:
10.4269/ajtmh.12-0456
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发表时间:
2013-04
期刊:
The American journal of tropical medicine and hygiene
影响因子:
--
通讯作者:
Overgaard HJ
Overgaard HJ
中科院分区:
其他
文献类型:
--
作者:
Haque U;Glass GE;Bomblies A;Hashizume M;Mitra D;Noman N;Haque W;Kabir MM;Yamamoto T;Overgaard HJ

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疟疾是孟加拉国的地方病。在这项纵向研究中,我们使用水文、地形和社会经济风险因素来解释个人和家庭层面的单次和多次疟疾感染。2009年和2010年,确定了54个村庄1 634个家庭的疟疾发病率。在整个研究期间,21.8%的家庭发现了所有(n = 497)疟疾病例; 15.4%的家庭有1例病例,6.4%的家庭有≥ 2例病例。疟疾感染的最大危险因素是每户蚊帐比率低、房屋建筑材料(墙壁)和房屋密度高。水文和地形因素与疟疾风险没有显着相关。这项研究确定了稳定的疟疾热点和风险因素,应考虑以具有成本效益的方式确定疟疾干预措施的目标,这可能有助于在孟加拉国消除疟疾。
Malaria is endemic to Bangladesh. In this longitudinal study, we used hydrologic, topographic, and socioeconomic risk factors to explain single and multiple malaria infections at individual and household levels. Malaria incidence was determined for 1,634 households in 54 villages in 2009 and 2010. During the entire study period 21.8% of households accounted for all (n = 497) malaria cases detected; 15.4% of households had 1 case and 6.4% had ≥ 2 cases. The greatest risk factors for malaria infection were low bed net ratio per household, house construction materials (wall), and high density of houses. Hydrologic and topographic factors were not significantly associated with malaria risk. This study identifies stable malaria hotspots and risk factors that should be considered for cost-effective targeting of malaria interventions that may contribute to potential elimination of malaria in Bangladesh.
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