Towards development of core domain sets for short term and long term studies of calcium pyrophosphate crystal deposition (CPPD) disease: A framework paper by the OMERACT CPPD working group.
Towards development of core domain sets for short term and long term studies of calcium pyrophosphate crystal deposition (CPPD) disease: A framework paper by the OMERACT CPPD working group.
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DOI：
10.1016/j.semarthrit.2021.04.019
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发表时间：
2021-08
影响因子：
5
通讯作者：
Dalbeth N
中科院分区：
文献类型：
--
作者：
Cai K;Fuller A;Zhang Y;Hensey O;Grossberg D;Christensen R;Shea B;Singh JA;McCarthy GM;Rosenthal AK;Filippou G;Taylor WJ;Diaz-Torne C;Stamp LK;Edwards NL;Pascart T;Becce F;Nielsen SM;Tugwell P;Beaton D;Abhishek A;Tedeschi SK;Dalbeth N
虽然焦磷酸钙沉积(CPPD)很常见，但对于CPPD的研究，还没有已公布的结果域或经过验证的测量工具。在这篇文章中，我们描述了风湿病结果测量(OMERACT)CPPD核心域集的开发框架。OMERACT CPPD工作组进行了范围界定的文献回顾和定性访谈研究。在2020年OMERACT CPPD虚拟特殊兴趣小组(SIG)会议上公布了生成的结果，讨论重点是是否应该为不同的焦磷酸钙沉积(CPPD)临床表现开发不同的核心域集，以及未来CPPD核心域集可能如何与已经建立的骨关节炎(OA)域重叠。在这些讨论的指导下，制定了OMERACT CPPD核心域集的未来工作计划。从112项研究的范围审查和对36人(28名慢性阻塞性肺病患者，7名卫生保健专业人员，1名利益相关者)的定性访谈研究中确定的领域被映射到OMERACT Filter 2.1的核心领域。大多数SIG与会者同意，有必要为CPPD的“短期”和“长期”研究制定单独的核心领域集。虽然CPPD+OA很常见，而且已经建立了OA的核心领域集合，但与会者一致认为，现有的OA核心领域集合不应影响CPPD的OMERACT核心领域集合的发展。优先排序练习(使用Delphi方法)将考虑40个用于CPPD短期研究的潜在领域和47个用于CPPD长期研究的潜在领域。OMERACT CPPD核心域集将针对急性CPP结晶性关节炎的个别发作和可能包括有任何CPPD临床表现(急性CPP结晶性关节炎、慢性CPP结晶性炎性关节炎和/或CPPD+OA)的参与者进行“短期”研究和“长期”研究。
Although calcium pyrophosphate deposition (CPPD) is common, there are no published outcome domains or validated measurement instruments for CPPD studies. In this paper, we describe the framework for development of the Outcome Measures in Rheumatology (OMERACT) CPPD Core Domain Sets. The OMERACT CPPD working group performed a scoping literature review and qualitative interview study. Generated outcomes were presented at the 2020 OMERACT CPPD virtual Special Interest Group (SIG) meeting with discussion focused on whether different core domain sets should be developed for different calcium pyrophosphate deposition (CPPD) clinical presentations and how the future CPPD Core Domain Set may overlap with already established osteoarthritis (OA) domains. These discussions informed development of a future work plan for development of the OMERACT CPPD Core Domain Sets. Domains identified from a scoping review of 112 studies and a qualitative interview study of 36 people (28 patients with CPPD, 7 health care professionals, one stakeholder) were mapped to core areas of OMERACT Filter 2.1. The majority of SIG participants agreed there was need to develop separate core domain sets for “short term” and “long term” studies of CPPD. Although CPPD + OA is common and core domain sets for OA have been established, participants agreed that existing OA core domain sets should not influence the development of OMERACT core domain sets for CPPD. Prioritization exercises (using Delphi methodology) will consider 40 potential domains for short term studies of CPPD and 47 potential domains for long term studies of CPPD. Separate OMERACT CPPD Core Domain Sets will be developed for “short term” studies for an individual flare of acute CPP crystal arthritis and for “long term” studies that may include participants with any clinical presentation of CPPD (acute CPP crystal arthritis, chronic CPP crystal inflammatory arthritis, and/or CPPD + OA).
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影响因子：
5
作者：
Cai K;Fuller A;Hensey O;Grossberg D;Christensen R;Shea B;Singh JA;Abhishek A;Tedeschi S;Dalbeth N
通讯作者：
Dalbeth N
影响因子：
27.4
作者：
Zhang, W.;Doherty, M.;Pascual, E.
通讯作者：
Pascual, E.
影响因子：
4.7
作者：
Abhishek, A.;Doherty, S.;Doherty, M.
通讯作者：
Doherty, M.
影响因子：
3.9
作者：
Smith, Toby O.;Hawker, Gillian A.;Conaghan, Philip G.
通讯作者：
Conaghan, Philip G.
DOI：
10.1056/nejmra1511117
发表时间：
2016-06-30
期刊：
The New England journal of medicine
影响因子：
--
作者：
Rosenthal AK;Ryan LM
通讯作者：
Ryan LM