City-wide school-located influenza vaccination: A retrospective cohort study.
City-wide school-located influenza vaccination: A retrospective cohort study.
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DOI：
10.1016/j.vaccine.2021.08.099
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发表时间：
2021-10-08
期刊：
影响因子：
5.5
通讯作者：
Colford JM Jr
中科院分区：
文献类型：
--
作者：
Benjamin-Chung J;Arnold BF;Mishra K;Kennedy CJ;Nguyen A;Pokpongkiat NN;Djajadi S;Seth A;Klein NP;Hubbard AE;Reingold A;Colford JM Jr
我们测量了在加州奥克兰市102所小学实施的全市学校流感疫苗接种（SLIV）计划的有效性。我们在2011年9月至2017年8月期间居住在干预中心或多变量匹配比较中心的所有年龄的Kaiser Permanente北方加州（KPNC）成员中进行了一项回顾性队列研究。结果包括医疗照顾的急性呼吸道疾病（MAARI），流感住院，和奥司他韦处方。我们使用广义线性模型估计了2014- 2015年、2015- 2016年和2016- 2017年的差异中的差异（DID），并根据种族、民族、年龄、性别、健康计划和语言进行了调整。不同研究中心的干预前成员特征相似。在干预期间，干预中心通过KPNC或SLIV计划接种流感疫苗的KPNC成员比例比对照中心高8-11%。在学龄儿童中，SLIV与每1,000人中奥司他韦处方量较低相关（DID：2015-16年-3.5（95%CI-5.5，-1.5）; 2016-17年-4.0（95%CI-6.5，-1.6）），但与其他结局无关。SLIV与65岁以上成年人中每1,000例MAARI较低相关（2014-15：−13.2，95%CI −23.2，−3.2; 2015-16：−21.5，95%CI −31.1，−11.9; 2016-17：−13.0，95%CI −23.2，−2.9）。在成年人中，与其他结果的显著关联很少。全市范围的SLIV干预与较高的流感疫苗接种覆盖率、学龄儿童中较低的奥司他韦处方和65岁以上人群中较低的MAARI相关，这表明SLIV可能对老年人产生间接影响。
We measured the effectiveness of a city-wide school-located influenza vaccination (SLIV) program implemented in over 102 elementary schools in Oakland, California. We conducted a retrospective cohort study among Kaiser Permanente Northern California (KPNC) members of all ages residing in either the intervention or a multivariate-matched comparison site from September 2011 - August 2017. Outcomes included medically attended acute respiratory illness (MAARI), influenza hospitalization, and Oseltamivir prescriptions. We estimated difference-in-differences (DIDs) in 2014–15, 2015–16, and 2016–17 using generalized linear models and adjusted for race, ethnicity, age, sex, health plan, and language. Pre-intervention member characteristics were similar between sites. The proportion of KPNC members vaccinated for influenza by KPNC or the SLIV program was 8–11% higher in the intervention site than the comparison site during the intervention period. Among school-aged children, SLIV was associated with lower Oseltamivir prescriptions per 1,000 (DIDs: −3.5 (95% CI −5.5, −1.5) in 2015–16; −4.0 (95% CI −6.5, −1.6) in 2016–17) but not with other outcomes. SLIV was associated with lower MAARI per 1,000 in adults 65 + years (2014–15: −13.2, 95% CI −23.2, −3.2; 2015–16: −21.5, 95% CI −31.1, −11.9; 2016–17: −13.0, 95% CI −23.2, −2.9). There were few significant associations with other outcomes among adults. A city-wide SLIV intervention was associated with higher influenza vaccination coverage, lower Oseltamivir prescriptions in school-aged children, and lower MAARI among people over 65 years, suggesting possible indirect effects of SLIV among older adults.
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影响因子：
19
作者：
Pebody, R. G.;Green, H. K.;Zambon, M.
通讯作者：
Zambon, M.
DOI：
10.1097/ede.0000000000000504
发表时间：
2016-09
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Arnold BF;Ercumen A;Benjamin-Chung J;Colford JM Jr
通讯作者：
Colford JM Jr
DOI：
10.1097/ede.0b013e3181d61eeb
发表时间：
2010-05
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Lipsitch M;Tchetgen Tchetgen E;Cohen T
通讯作者：
Cohen T
影响因子：
8
作者：
Davis, Mollie M.;King, James C., Jr.;Magder, Laurence S.
通讯作者：
Magder, Laurence S.
影响因子：
1.8
作者：
Freedman, David A.
通讯作者：
Freedman, David A.