Peanut allergy and anaphylaxis.

Peanut allergy and anaphylaxis.
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DOI:
10.1016/j.coi.2010.10.005
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发表时间:
2010-12
影响因子:
7
通讯作者:
Finkelman FD
Finkelman FD
中科院分区:
医学2区
文献类型:
--
作者:
Finkelman FD

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Peanuts are a frequent cause of food allergy and the most common cause of fatal food-induced anaphylaxis in the U.S. Advances during the past two years have promoted our understanding of peanut allergens and peanut allergy prevalence, etiology, diagnosis and therapy. The advances highlighted in this review include evidence that the peanut allergens most important in disease differ in different parts of the world, that early oral exposure to peanuts may decrease the frequency of peanut allergy, while early non-oral exposure may have the opposite effect, that complement activation by peanut constituents appears to promote peanut-induced anaphylaxis and that oral immunotherapy, anti-IgE antibody and an herbal formulation are promising approaches for treatment of this disorder.
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