Effective motion-sensitizing magnetization preparation for black blood magnetic resonance imaging of the heart.
Effective motion-sensitizing magnetization preparation for black blood magnetic resonance imaging of the heart.
复制标题
DOI：
10.1002/jmri.21568
复制
发表时间：
2008-11
影响因子：
4.4
通讯作者：
Wang, Yi
中科院分区：
文献类型：
--
作者：
Nguyen, Thanh D.;de Rochefort, Ludovic;Spincemaille, Pascal;Cham, Matthew D.;Weinsaft, Jonathan W.;Prince, Martin R.;Wang, Yi
目的探讨运动敏化磁化准备(MSPREP)序列对血流信号的抑制效果，并优化二维运动敏化磁化准备(MSPREP)稳态自由进动(SSFP)序列用于心脏黑血成像。利用流动体模，研究了不同速度场(FOS)、b值、体素尺寸和流型对流动抑制的影响。用MSPREP-SSFP和双反转恢复快速自旋回波(DIR-FSE)技术对7名健康志愿者进行了1.5T心脏黑血成像。测定心肌和血液的信噪比(SNR)和心肌与血液的对比噪声比(CNR)。确定了使MSPREP-SSFP的CNR最大化的最佳FOS。体模数据表明，速度编码效应是导致流动抑制的主要原因。在人类，FOS=10-20 cm/S被发现在短轴(SA)和四腔(4C)切面的CNR最大。与DIR-FSE相比，MSPREP-SSFP在SA基础和中位切面具有相似的血液信噪比效率，而在SA心尖(P=0.02)和4C(P=0.01)切面的血液SNR效率显著降低，显示相似或更好的血液抑制。速度编码是MSPREP序列的主要血流抑制机制，2DMSPREP-SSFP心脏黑血成像在健康受试者中是可行的。
To investigate the effectiveness of flow signal suppression of a motion-sensitizing magnetization preparation (MSPREP) sequence and to optimize a 2D MSPREP steady-state free precession (SSFP) sequence for black blood imaging of the heart. Using a flow phantom, the effect of varying field of speed (FOS), b-value, voxel size, and flow pattern on the flow suppression was investigated. In seven healthy volunteers, black blood images of the heart were obtained at 1.5T with MSPREP-SSFP and double inversion recovery fast spin echo (DIR-FSE) techniques. Myocardium and blood signal-to-noise ratio (SNR) and myocardium-to-blood contrast-to-noise ratio (CNR) were measured. The optimal FOS that maximized the CNR for MSPREP-SSFP was determined. Phantom data demonstrated that the flow suppression was induced primarily by the velocity encoding effect. In humans, FOS = 10-20 cm/s was found to maximize the CNR for short-axis (SA) and four-chamber (4C) views. Compared to DIR-FSE, MSPREP-SSFP provided similar blood SNR efficiency in the SA basal and mid views and significantly lower blood SNR efficiency in the SA apical (P = 0.02) and 4C (P = 0.01) views, indicating similar or better blood suppression. Velocity encoding is the primary flow suppression mechanism of the MSPREP sequence and 2D MSPREP-SSFP black blood imaging of the heart is feasible in healthy subjects.
登录
查看更多内容
影响因子：
3.3
作者：
Nguyen, Thanh D.;Spincemaille, Pascal;Wang, Yi
通讯作者：
Wang, Yi
影响因子：
3.3
作者：
de Rochefort, L;Maître, X;Durand, E
通讯作者：
Durand, E
影响因子：
4.4
作者：
Deshpande, VS;Shea, SM;Li, DB
通讯作者：
Li, DB
影响因子：
4.4
作者：
Nayak, KS;Rivas, PA;Nishimura, DG
通讯作者：
Nishimura, DG
影响因子：
37.8
作者：
Sirol, M;Itskovich, VV;Fayad, ZA
通讯作者：
Fayad, ZA