The frequency of pregnancy and exposure to cytomegalovirus infections among women with a young child in day care.
The frequency of pregnancy and exposure to cytomegalovirus infections among women with a young child in day care.
复制标题
DOI：
10.1016/j.ajog.2008.08.037
复制
发表时间：
2009-02
影响因子：
9.8
通讯作者：
Adler, Stuart P.
中科院分区：
文献类型：
--
作者：
Marshall, Beth C.;Adler, Stuart P.
旨在确定考虑可能再次怀孕的母亲以及在团体日托机构中生有 2 岁以下儿童的母亲的怀孕频率和 CMV 暴露情况。我们进行了一项前瞻性观察研究，其中包括对日托中心的母亲及其孩子进行人口调查问卷以及血清学和病毒学监测。在 60 名女性中，62% 的血清呈阴性，20% 的孩子排出了 CMV。在 60 名女性中，23 名女性或 38% (95% CI = 0.27, 0.51) 平均在入组后 10 个月内怀孕。在怀孕期间，这些孕妇中有 8 % 或 35% (95% CI = 0.19, 0.55) 的孩子在日托中心生下了 CMV。这些结果说明了与怀孕期间接触无声病毒感染相关的公共问题的潜在严重性。我们的数据推算到美国人口后，估计每两年就有 31,000 至 168,000 名易感孕妇将因受感染的儿童而接触 CMV。
To determine the frequency of pregnancy and exposure to CMV among mothers contemplating a possible additional pregnancy and with a child less than 2 years of age in group day care. We performed a prospective observational study which included a demographic questionnaire and serologic and virologic monitoring of mothers and their children in day care. Of 60 women, 62% were seronegative and 20% had a child shedding CMV. Of the 60 women, 23 women or 38% (95% CI = 0.27, 0.51) became pregnant on average 10 months after enrollment. During pregnancy, eight or 35% (95% CI = 0.19, 0.55) of these pregnant women had a child in day care who shed CMV These results illustrate the potential magnitude of the public problem associated with exposure to a silent viral infection during pregnancy. Our data, when extrapolated to the U.S. population, estimate that every two years between 31,000 and 168,000 susceptible pregnant women will be exposed to CMV by an infected child.
登录
查看更多内容
影响因子：
5.1
作者：
Adler, SP;Finney, JW;Best, AM
通讯作者：
Best, AM
影响因子：
6.4
作者：
Wang, JB;Adler, SP;Plotkin, SA
通讯作者：
Plotkin, SA
影响因子：
1.8
作者：
Agresti, A;Coull, BA
通讯作者：
Coull, BA
影响因子：
4.5
作者：
Cannon MJ;Davis KF
通讯作者：
Davis KF
影响因子：
3.6
作者：
HUTTO, C;RICKS, R;PASS, RF
通讯作者：
PASS, RF