Label-free quantitative optical assessment of human colon tissue using spatial frequency domain imaging.
Label-free quantitative optical assessment of human colon tissue using spatial frequency domain imaging.
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使用空间频域成像对人类结肠组织的无标记定量光学评估。
DOI：
10.1007/s10151-018-1841-y
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发表时间：
2018-08
影响因子：
3.3
通讯作者：
Zhu Q
中科院分区：
文献类型：
--
作者：
Nandy S;Chapman W Jr;Rais R;González I;Chatterjee D;Mutch M;Zhu Q
结直肠癌仍然是全球诊断的第二大常见恶性肿瘤，在美国每年有超过100，000例新发病例[1]。目前的治疗方法通常涉及手术切除，并根据疾病部位和阶段选择性使用放射和化疗。然而，一些最大的生存收益来自积极的内窥镜筛查。特别是结肠镜检查可以在早期发现结直肠恶性疾病，同时也提供了包括切除早期肿瘤疾病在内的治疗选择[2]。然而，一些情况仍然使内窥镜监测复杂化，包括识别和评估扁平肿瘤，如无蒂息肉和新辅助治疗后的肿瘤再分期;这些可以隐藏早期癌症，但仍然难以用标准内窥镜技术识别。此外，新辅助治疗后残留直肠癌的粘膜定量评价仍然非常困难，使用柔性或刚性内窥镜技术。区分无菌性瘢痕和隐匿性残留恶性肿瘤是最重要的因素之一
Colorectal cancer remains the second most common malignancy diagnosed worldwide and accounts for over 100,000 new cases annually in the US [1]. Current treatment methods typically involve surgical resection with selective use of radiation and chemotherapy depending on disease site and stage. Some of the greatest gains in survival, however, have come from aggressive endoscopic screening. In particular, colonoscopy has led to detection of colorectal malignant disease at an earlier stage while also providing therapeutic options including resection of early neoplastic disease [2].However, several scenarios continue to complicate endoscopic surveillance including identification and assessment of flat neoplasia like sessile polyps and oncologic restaging following neoadjuvant therapy; these can harbor early cancers but remain difficult to identify with standard endoscopic techniques. Additionally, quantitative evaluation of the mucosa for residual rectal cancer after neoadjuvant treatment remains exceedingly difficult using flexible or rigid endoscopic technology. Differentiating a sterile scar from occult residual malignancy is one of the greatest factors
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影响因子：
9.8
作者：
Rex, Douglas K.;Ahnen, Dennis J.;Baron, John A.;Batts, Kenneth P.;Burke, Carol A.;Burt, Randall W.;Goldblum, John R.;Guillem, Jose G.;Kahi, Charles J.;Kalady, Matthew F.;O'Brien, Michael J.;Odze, Robert D.;Ogino, Shuji;Parry, Susan;Snover, Dale C.;Torlakovic, Emina Emilia;Wise, Paul E.;Young, Joanne;Church, James
通讯作者：
Church, James
DOI：
10.1186/bcr3455
发表时间：
2013
期刊：
Breast cancer research : BCR
影响因子：
--
作者：
Laughney AM;Krishnaswamy V;Rizzo EJ;Schwab MC;Barth RJ Jr;Cuccia DJ;Tromberg BJ;Paulsen KD;Pogue BW;Wells WA
通讯作者：
Wells WA
影响因子：
254.7
作者：
Siegel, Rebecca L.;Miller, Kimberly D.;Jemal, Ahmedin
通讯作者：
Jemal, Ahmedin
DOI：
10.1038/ajg.2015.418
发表时间：
2016-03
期刊：
The American journal of gastroenterology
影响因子：
--
作者：
Pan J;Xin L;Ma YF;Hu LH;Li ZS
通讯作者：
Li ZS
影响因子：
3.4
作者：
Nandy, Sreyankar;Hagemann, Ian S.;Zhu, Quing
通讯作者：
Zhu, Quing