A new method of measuring the amount of soft tissue in pulmonary ground-glass opacity nodules: a phantom study.
A new method of measuring the amount of soft tissue in pulmonary ground-glass opacity nodules: a phantom study.
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DOI：
10.3348/kjr.2008.9.3.219
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发表时间：
2008-05
影响因子：
4.8
通讯作者：
Dae CM
中科院分区：
文献类型：
--
作者：
Lee KW;Im JG;Kim TJ;Dae CM
设计一种新的方法来测量肺磨玻璃样阴影结节中软组织的数量，并通过使用体模研究将该方法的使用与先前的体积测量方法进行比较。用固定的正常猪肺材料制备体模结节。40个结节，每个直径为10 mm，具有可变的平均衰减。结节中软组织的参考标准量通过重量除以比重获得。使用16通道多探测器CT扫描仪获取关于体模结节的成像数据。CT测量的结节软组织量计算如下：软组织量=体积×（1 +平均衰减值/1，000）。还测量了软组织的CT测量量与软组织的参考标准量之间的相对百分比误差（RPE）。通过配对t检验，将使用新方法测定的RPE与使用当前容量测量方法测定的RPE进行比较。CT测量的软组织量显示出与软组织的参考标准量的强相关性（R2 = 0.996，p < 0.01）。CT测量结节内软组织量的平均RPE为-7.79 ± 1.88%。CT测量体积的平均RPE为114.78 ± 51.02%，明显大于CT测量软组织体积的RPE（p < 0.01）。使用CT测量的软组织量比使用CT测量的体积更准确地反映了毛玻璃样结节中软组织的参考标准量。
To devise a new method to measure the amount of soft tissue in pulmonary ground-glass opacity nodules, and to compare the use of this method with a previous volumetric measurement method by use of a phantom study. Phantom nodules were prepared with material from fixed normal swine lung. Forty nodules, each with a diameter of 10 mm, were made with a variable mean attenuation. The reference-standard amount of soft tissue in the nodules was obtained by dividing the weight by the specific gravity. The imaging data on the phantom nodules were acquired with the use of a 16-channel multidetector CT scanner. The CT-measured amount of soft tissue of the nodules was calculated as follows: soft tissue amount = volume × (1 + mean attenuation value / 1,000). The relative percentage error (RPE) between the CT-measured amount of the soft tissue and the reference-standard amount of the soft tissue was also measured. The RPEs determined with use of the new method were compared with the RPEs determined with the current volumetric measurement method by the use of the paired t test. The CT-measured amount of soft tissue showed a strong correlation with the reference-standard amount of soft tissue (R2 = 0.996, p < 0.01). The mean RPE of the CT-measured amount of soft tissue in the nodules was -7.79 ± 1.88%. The mean RPE of the CT-measured volume was 114.78 ± 51.02%,which was significantly greater than the RPE of the CT-measured amount of soft tissue (p < 0.01). The amount of soft tissue measured by the use of CT reflects the reference-standard amount of soft tissue in the ground-glass opacity nodules much more accurately than does the use of the CT-measured volume.
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影响因子：
4.8
作者：
Lee HJ;Goo JM;Lee CH;Yoo CG;Kim YT;Im JG
通讯作者：
Im JG
DOI：
10.1164/ajrccm.163.6.2005001
发表时间：
2001-05-01
影响因子：
24.7
作者：
Malbouisson, LM;Muller, JC;Rouby, JJ
通讯作者：
Rouby, JJ
影响因子：
4.8
作者：
Goo JM;Lee JW;Lee HJ;Kim S;Kim JH;Im JG
通讯作者：
Im JG
影响因子：
3.3
作者：
Marten, K;Funke, M;Engelke, C
通讯作者：
Engelke, C
影响因子：
19.7
作者：
Revel, MP;Lefort, C;Frija, G
通讯作者：
Frija, G