Seasonal control of gonadotropin-inhibitory hormone (GnIH) in birds and mammals.

Seasonal control of gonadotropin-inhibitory hormone (GnIH) in birds and mammals.
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鸟类和哺乳动物中促性腺激素抑制激素(GnIH)的季节性调控

DOI:
10.1016/j.yfrne.2014.12.001
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发表时间:
2015-04
影响因子:
7.4
通讯作者:
Tsutsui, Kazuyoshi
Tsutsui, Kazuyoshi
中科院分区:
医学1区
文献类型:
--
作者:
Kriegsfeld, Lance J.;Ubuka, Takayoshi;Bentley, George E.;Tsutsui, Kazuyoshi

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生活在温带和北半球的动物,其环境质量会发生明显的季节性变化,并通过在一年中最有利的时间进行繁殖活动来最大限度地提高繁殖成功率。虽然驱动生殖功能季节性变化的具体机制在不同物种之间存在差异,但越来越多的证据表明,促性腺激素抑制激素(GnIH)是某些物种中驱动生殖和性动机季节性变化的神经内分泌回路的关键组成部分。除了通过光周期信息的转导预测环境变化并相应地修改生殖状态外,GnIH还可以在全年出现不可预测的条件时调节生殖状态的急剧变化。本综述总结了GnIH在鸟类和哺乳动物季节性繁殖中的作用,同时考虑到在繁殖光周期物种的广泛调查中出现的相似性和差异。
Animals inhabiting temperate and boreal latitudes experience marked seasonal changes in the quality of their environments and maximize reproductive success by phasing breeding activities with the most favorable time of year. Whereas the specific mechanisms driving seasonal changes in reproductive function vary across species, converging lines of evidence suggest gonadotropin-inhibitory hormone (GnIH) serves as a key component of the neuroendocrine circuitry driving seasonal changes in reproduction and sexual motivation in some species. In addition to anticipating environmental change through transduction of photoperiodic information and modifying reproductive state accordingly, GnIH is also positioned to regulate acute changes in reproductive status should unpredictable conditions manifest throughout the year. The present overview summarizes the role of GnIH in avian and mammalian seasonal breeding while considering the similarities and disparities that have emerged from broad investigations across reproductively photoperiodic species.
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