Electrospun fibrous scaffolds with multiscale and photopatterned porosity.
Electrospun fibrous scaffolds with multiscale and photopatterned porosity.
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DOI：
10.1002/mabi.200900363
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发表时间：
2010-03-10
影响因子：
4.6
通讯作者：
Burdick, Jason A.
中科院分区：
文献类型：
--
作者：
Sundararaghavan, Harini G.;Metter, Robert B.;Burdick, Jason A.
组织工程环境的结构和机械特性对于成功的细胞生长和组织修复至关重要。静电纺丝在组织工程支架的制造中受到广泛关注，但这些支架的小孔径限制了细胞浸润和构建血管化。为了解决这个问题，我们将静电纺丝与光图案化相结合来创建多尺度多孔支架。与无图案支架相比，该过程保留了支架的纤维性质，并允许增强的细胞浸润和血管化。这是光图案首次与电纺支架一起使用，并且现在只有通过反应性大分子单体的静电纺丝才能实现。
The structural and mechanical properties of tissue engineered environments are crucial for successful cellular growth and tissue repair. Electrospinning is gaining wide attention for the fabrication of tissue engineered scaffolds, but the small pore sizes of these scaffolds limit cell infiltration and construct vascularization. To address this problem, we have combined electrospinning with photopatterning to create multi-scale porous scaffolds. This process retains the fibrous nature of the scaffolds and permits enhanced cellular infiltration and vascularization when compared to unpatterned scaffolds. This is the first time that photopatterning has been utilized with electrospun scaffolds and is only now possible with the electrospinning of reactive macromers.
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影响因子：
14
作者：
Bryant, Stephanie J.;Cuy, Janet L.;Ratner, Buddy D.
通讯作者：
Ratner, Buddy D.
影响因子：
14
作者：
Lee, Soo-Hong;Moon, James J.;West, Jennifer L.
通讯作者：
West, Jennifer L.
影响因子：
14
作者：
Ji, Y;Ghosh, K;Rafailovich, MH
通讯作者：
Rafailovich, MH
影响因子：
10.8
作者：
Sun, DH;Chang, C;Lin, LW
通讯作者：
Lin, LW
DOI：
10.1111/j.1440-1746.2008.05530.x
发表时间：
2009-02-01
影响因子：
4.1
作者：
Kazemnejad, Somaieh;Allameh, Abdolamir;Jazayery, Maryam
通讯作者：
Jazayery, Maryam