Convergent genomic signatures of domestication in sheep and goats.
Convergent genomic signatures of domestication in sheep and goats.
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DOI：
10.1038/s41467-018-03206-y
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发表时间：
2018-03-06
影响因子：
16.6
通讯作者：
Pompanon F
中科院分区：
文献类型：
--
作者：
Alberto FJ;Boyer F;Orozco-terWengel P;Streeter I;Servin B;de Villemereuil P;Benjelloun B;Librado P;Biscarini F;Colli L;Barbato M;Zamani W;Alberti A;Engelen S;Stella A;Joost S;Ajmone-Marsan P;Negrini R;Orlando L;Rezaei HR;Naderi S;Clarke L;Flicek P;Wincker P;Coissac E;Kijas J;Tosser-Klopp G;Chikhi A;Bruford MW;Taberlet P;Pompanon F
驯化的进化基础一直是一个长期存在的问题，随着越来越多的家养物种成为基因组激活的物种，驯化的遗传结构变得越来越容易处理。在世界范围内建立之前，绵羊和山羊在距今10，500年前（YBP）的肥沃新月中被驯化，它们的野生亲戚仍然存在。在这里，我们测序的野生亚洲山羊和牛黄北山羊的基因组在绵羊和山羊驯化中心，并比较它们的基因组与地方，传统和改良品种的山羊。在携带区分家养品种和野生种群的选择性扫描的基因组区域中，其中20个与涉及神经系统、免疫力和生产力性状的基因有关，这20个是山羊和绵羊共有的。物种之间的选择模式各不相同，这表明虽然存在与驯化和改良相关的选择的共同目标，但已经出现了不同的解决方案，以在这些密切相关的牲畜物种中实现相似的表型终点。绵羊和山羊在大约10，500年前在中东的同一地区被驯化。在这里，Alberto等人比较了野生亚洲山羊和牛黄野山羊的基因组与来自当地、传统和改良品种的山羊的基因组，并发现了与绵羊和山羊的驯化和改良相关的共同选择目标。
The evolutionary basis of domestication has been a longstanding question and its genetic architecture is becoming more tractable as more domestic species become genome-enabled. Before becoming established worldwide, sheep and goats were domesticated in the fertile crescent 10,500 years before present (YBP) where their wild relatives remain. Here we sequence the genomes of wild Asiatic mouflon and Bezoar ibex in the sheep and goat domestication center and compare their genomes with that of domestics from local, traditional, and improved breeds. Among the genomic regions carrying selective sweeps differentiating domestic breeds from wild populations, which are associated among others to genes involved in nervous system, immunity and productivity traits, 20 are common to Capra and Ovis. The patterns of selection vary between species, suggesting that while common targets of selection related to domestication and improvement exist, different solutions have arisen to achieve similar phenotypic end-points within these closely related livestock species. The sheep and goat were domesticated ~10,500 years ago in the same region of the Middle-East. Here, Alberto et al compare the genomes of wild Asiatic mouflon and Bezoar ibex with that of domestics from local, traditional and improved breeds and find common targets of selection related to domestication and improvement in sheep and goats.
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DOI：
10.1126/science.1252806
发表时间：
2014-06-06
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Jiang Y;Xie M;Chen W;Talbot R;Maddox JF;Faraut T;Wu C;Muzny DM;Li Y;Zhang W;Stanton JA;Brauning R;Barris WC;Hourlier T;Aken BL;Searle SMJ;Adelson DL;Bian C;Cam GR;Chen Y;Cheng S;DeSilva U;Dixen K;Dong Y;Fan G;Franklin IR;Fu S;Guan R;Highland MA;Holder ME;Huang G;Ingham AB;Jhangiani SN;Kalra D;Kovar CL;Lee SL;Liu W;Liu X;Lu C;Lv T;Mathew T;McWilliam S;Menzies M;Pan S;Robelin D;Servin B;Townley D;Wang W;Wei B;White SN;Yang X;Ye C;Yue Y;Zeng P;Zhou Q;Hansen JB;Kristensen K;Gibbs RA;Flicek P;Warkup CC;Jones HE;Oddy VH;Nicholas FW;McEwan JC;Kijas J;Wang J;Worley KC;Archibald AL;Cockett N;Xu X;Wang W;Dalrymple BP
通讯作者：
Dalrymple BP
影响因子：
64.8
作者：
Li, Heng;Durbin, Richard
通讯作者：
Durbin, Richard
使用下一代 DNA 测序数据进行变异发现和基因分型的框架。
影响因子：
30.8
作者：
通讯作者：
--
影响因子：
9.8
作者：
Kijas JW;Lenstra JA;Hayes B;Boitard S;Porto Neto LR;San Cristobal M;Servin B;McCulloch R;Whan V;Gietzen K;Paiva S;Barendse W;Ciani E;Raadsma H;McEwan J;Dalrymple B;International Sheep Genomics Consortium Members
通讯作者：
International Sheep Genomics Consortium Members
影响因子：
3.1
作者：
BELYAEV, DK
通讯作者：
BELYAEV, DK