Viruses associated with acute respiratory infections and influenza-like illness among outpatients from the Influenza Incidence Surveillance Project, 2010-2011.
Viruses associated with acute respiratory infections and influenza-like illness among outpatients from the Influenza Incidence Surveillance Project, 2010-2011.
复制标题
DOI：
10.1093/infdis/jit806
复制
发表时间：
2014-06-01
期刊：
影响因子：
--
通讯作者：
IISP Working Group
中科院分区：
文献类型：
--
作者：
Fowlkes A;Giorgi A;Erdman D;Temte J;Goodin K;Di Lonardo S;Sun Y;Martin K;Feist M;Linz R;Boulton R;Bancroft E;McHugh L;Lojo J;Filbert K;Finelli L;IISP Working Group
背景。流感发病率监测项目（IISP）监测门诊急性呼吸道感染（ARI，定义为存在≥2种不符合ILI标准的呼吸道症状）和流感样疾病（ILI），以确定相关病毒病因的发病率和贡献。方法。从2010年8月到2011年7月，美国12个地点的57家门诊医疗服务提供者每周报告ILI和ARI就诊次数，并收集呼吸道样本进行病毒检测。发病率以就诊患者数为分母估计，就诊病毒特异性发病率由检测呈阳性的患者比例外推。结果。经年龄调整的ARI和ILI门诊累计发病率为95/1000人，在58%的标本中确定了病毒病因。最常检测到的是鼻病毒/肠病毒（RV/EV）（21%）和流感病毒（21%）；由此推断的门诊就诊发生率分别为20 /1000和19/1000。流感病毒相关的门诊就诊发生率在2-17岁的患者中最高，而其他病毒在不同年龄组之间有不同的模式。结论。IISP提供了一个独特的机会，估计门诊呼吸道疾病负担的病因。流感病毒感染和RV/EV感染是美国门诊呼吸道疾病的主要负担，尤其是儿童。
Background. The Influenza Incidence Surveillance Project (IISP) monitored outpatient acute respiratory infection (ARI; defined as the presence of ≥2 respiratory symptoms not meeting ILI criteria) and influenza-like illness (ILI) to determine the incidence and contribution of associated viral etiologies. Methods. From August 2010 through July 2011, 57 outpatient healthcare providers in 12 US sites reported weekly the number of visits for ILI and ARI and collected respiratory specimens on a subset for viral testing. The incidence was estimated using the number of patients in the practice as the denominator, and the virus-specific incidence of clinic visits was extrapolated from the proportion of patients testing positive. Results. The age-adjusted cumulative incidence of outpatient visits for ARI and ILI combined was 95/1000 persons, with a viral etiology identified in 58% of specimens. Most frequently detected were rhinoviruses/enteroviruses (RV/EV) (21%) and influenza viruses (21%); the resulting extrapolated incidence of outpatient visits was 20 and 19/1000 persons respectively. The incidence of influenza virus-associated clinic visits was highest among patients aged 2–17 years, whereas other viruses had varied patterns among age groups. Conclusions. The IISP provides a unique opportunity to estimate the outpatient respiratory illness burden by etiology. Influenza virus infection and RV/EV infection(s) represent a substantial burden of respiratory disease in the US outpatient setting, particularly among children.
登录
查看更多内容
影响因子：
11.8
作者：
Fry, Alicia M.;Curns, Aaron T.;Anderson, Larry J.
通讯作者：
Anderson, Larry J.
影响因子：
11.8
作者：
Neuzil, KM;Maynard, C;Heagerty, P
通讯作者：
Heagerty, P
影响因子：
11.8
作者：
Glaser CA;Gilliam S;Thompson WW;Dassey DE;Waterman SH;Saruwatari M;Shapiro S;Fukuda K
通讯作者：
Fukuda K
DOI：
10.1016/s1386-6532(07)70006-9
发表时间：
2007-11
期刊：
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
影响因子：
--
作者：
Fox JD
通讯作者：
Fox JD
影响因子：
12.7
作者：
Falchi, Alessandra;Turbelin, Clement;Carrat, Fabrice
通讯作者：
Carrat, Fabrice