The Upsides and Downsides of Organelle Interconnectivity.
The Upsides and Downsides of Organelle Interconnectivity.
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DOI:
10.1016/j.cell.2017.02.030
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发表时间:
2017-03-23
期刊:
影响因子:
64.5
通讯作者:
Nyström T
中科院分区:
文献类型:
--
作者:
Gottschling DE;Nyström T
Interconnectivity and feedback control are hallmarks of biological systems. This includes communication between organelles, which allows them to function and adapt to changing cellular environments. While the specific mechanisms for all communications remain opaque, unraveling the wiring of organelle networks is critical to understand how biological systems are built and why they might collapse, as occurs in aging. A comprehensive understanding of all the routes involved in inter-organelle communication is still lacking but important themes are beginning to emerge, primarily in budding yeast. These routes are reviewed here in the context of sub-system proteostasis and Complex Adaptive Systems theory.
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DOI:
10.1007/978-1-61779-276-2_8
发表时间:
2011-01-01
期刊:
NETWORK BIOLOGY: METHODS AND APPLICATIONS
影响因子:
--
作者:
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通讯作者:
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DOI:
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发表时间:
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期刊:
The Journal of cell biology
影响因子:
--
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通讯作者:
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影响因子:
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作者:
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影响因子:
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