Prevalence of alcohol-associated liver disease: a systematic review and meta-analysis.
Prevalence of alcohol-associated liver disease: a systematic review and meta-analysis.
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DOI：
10.1097/hc9.0000000000000133
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发表时间：
2023-05-01
影响因子：
5.1
通讯作者：
Parker, Richard
中科院分区：
文献类型：
--
作者：
Amonker, Sachin;Houshmand, Aryo;Hinkson, Alexander;Rowe, Ian;Parker, Richard
酒精相关性肝病（ALD）是发病和过早死亡的常见原因。到目前为止，还没有系统的综合ALD的患病率。这项系统性综述的目的是报告不同医疗保健环境中ALD的患病率。在PubMed和EMBASE中检索报告ALD在接受通用检测过程的人群中患病率的研究。进行单比例荟萃分析，以估计所有ALD，酒精相关性脂肪肝和酒精相关性肝硬化的患病率，在酒精使用障碍（AUD）患者中，酒精使用障碍人群，初级保健。纳入了35项研究，报告了513，278例患者，包括5968例ALD，18，844例酒精相关性脂肪肝和502例酒精相关性肝硬化。在COPD人群中，ALD的患病率为3.5%（95%CI，2.0%-6.0%），初级保健的患病率为2.6%（0.5%-11.7%），AUD组的患病率为51.0%（11.1%-89.3%）。酒精相关性肝硬化的患病率在一般人群中为0.3%（0.2%-0.4%），在初级保健中为1.7%（0.3%-10.2%），在AUD组中为12.9%（4.3%-33.2%）。酒精性肝病或肝硬化在一般人群和初级保健中并不常见，但在合并AUD的患者中非常常见。肝病的靶向干预措施，如病例发现，将在高危人群中更有效。
Alcohol-associated liver disease (ALD) is a common cause of morbidity and premature mortality. To date, there has been no systematic synthesis of the prevalence of ALD. This systematic review was done with the aim of reporting the prevalence of ALD across different health care settings. PubMed and EMBASE were searched for studies reporting the prevalence of ALD in populations subjected to a universal testing process. Single-proportion meta-analysis was performed to estimate the prevalence of all ALD, alcohol-associated fatty liver, and alcohol-associated cirrhosis, in unselected populations, primary care, and among patients with alcohol-use disorder (AUD). Thirty-five studies were included reporting on 513,278 persons, including 5968 cases of ALD, 18,844 cases of alcohol-associated fatty liver, and 502 cases of alcohol-associated cirrhosis. In unselected populations, the prevalence of ALD was 3.5% (95% CI, 2.0%–6.0%), the prevalence in primary care was 2.6% (0.5%–11.7%), and the prevalence in groups with AUD was 51.0% (11.1%–89.3%). The prevalence of alcohol-associated cirrhosis was 0.3% (0.2%–0.4%) in general populations, 1.7% (0.3%–10.2%) in primary care, and 12.9% (4.3%–33.2%) in groups with AUD. Liver disease or cirrhosis due to alcohol is not common in general populations and primary care but very common among patients with coexisting AUD. Targeted interventions for liver disease such as case finding will be more effective in at-risk populations.
影响因子：
0.5
作者：
Chaudhary, Ashlesha;Chaudhary, Arun Kumar;Chaudhary, Aashutosh;Bhandari, Abashesh;Dahal, Sujata;Bhusal, Suzit
通讯作者：
Bhusal, Suzit
DOI：
10.11604/pamj.2013.15.23.2040
发表时间：
2013
期刊：
The Pan African medical journal
影响因子：
--
作者：
Opio CK;Seremba E;Ocama P;Lalitha R;Kagimu M;Lee WM
通讯作者：
Lee WM
影响因子：
1.4
作者：
Nagappa B;Ramalingam A;Rastogi A;Dubey S;Thomas SS;Gupta E;Sarin SK
通讯作者：
Sarin SK