Exercise and Reduced Nicotine Content Cigarettes in Adult Female Smokers: A Pilot Trial.
Exercise and Reduced Nicotine Content Cigarettes in Adult Female Smokers: A Pilot Trial.
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DOI：
10.3390/ijerph19116647
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发表时间：
2022-05-29
影响因子：
--
通讯作者：
Malin, Steven K.
中科院分区：
文献类型：
--
作者：
Li, Chaofan;Yao, Nengliang;Miller, Stephanie L.;Macpherson, Christopher;Hassinger, Taryn;Love, Kaitlin;Malin, Steven K.
背景：虽然减少尼古丁香烟(RNC)被认为可以改善戒烟和心脏代谢健康，但与RNC一起进行的运动训练对戒烟和心脏代谢健康的效果尚不清楚。方法：将27例女性吸烟者随机分为：(1)普通尼古丁香烟组(即对照组)、(2)RNC组和(3)RNC加运动治疗组，治疗12周。观察治疗前后的戒烟症状(如威斯康星戒烟量表)和心脏代谢健康状况(如体重、最大摄氧量、静息呼吸交换率、血糖、HOMA-IR)。结果：治疗对体重(p=0.80，偏η2=0.2 9)、最大摄氧量(p=0.2 0，偏η2=0.18)或总胆固醇/高密度脂蛋白比值(p=0.5 9，偏η2=0.0 6)无明显影响。然而，与对照组和对照组相比，RNC+运动组倾向于维持RER(即脂肪氧化；p=0.10，部分η2=0.10)以及胰岛素抵抗(p=0.13，部分η2=0.2 5)和皮质醇(p=0.0 6，部分η2=0.30)。最大摄氧量增加也与尼古丁依赖评分降低有关(r=−0.50，p<；0.05)。结论：在这项初步研究中，健康状况的改善与尼古丁依赖度的降低有关。有必要开展更多的工作，以检查运动对吸烟者的影响，将其作为促进戒烟和降低疾病风险的工具。
Background: Although Reduced Nicotine Cigarettes (RNC) are suggested to improve smoking cessation and cardiometabolic health in relation to cancer risk, the effectiveness of exercise training with RNC on smoking cessation and cardiometabolic health is unknown. Methods: Female smokers (N = 27) were randomized to: (1) usual nicotine cigarettes (i.e., control), (2) RNC or (3) RNC plus exercise treatment for 12 weeks. Smoking withdrawal symptoms (e.g., Wisconsin Smoking Withdrawal Scale) and cardiometabolic health (e.g., weight, VO2max, resting respiratory exchange ratio (RER), glucose, HOMA-IR) were examined before and after treatment. Results: Treatments had no differential effect on weight (p = 0.80; partial η2 = 0.29), VO2max (p = 0.20, partial η2 = 0.18), or total cholesterol/HDL ratios (p = 0.59, partial η2 = 0.06). However, RNC + Exercise tended to maintain RER (i.e., fat oxidation; p = 0.10, partial η2 = 0.10) as well as insulin resistance (p = 0.13, partial η2 = 0.25) and cortisol compared (p = 0.06, partial η2 = 0.30) with control and RNC. Increased VO2max was also associated with lower nicotine dependence scores (r = −0.50, p < 0.05). Conclusion: In this pilot study, improved fitness was associated with lower nicotine dependence. Additional work is warranted to examine the effects of exercise in smokers as a tool to improving smoking cessation and lower disease risk.
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影响因子：
39.2
作者：
KAWACHI, I;COLDITZ, GA;SPEIZER, FE
通讯作者：
SPEIZER, FE
影响因子：
6
作者：
Hatsukami, Dorothy K.;Kotlyar, Michael;Hecht, Stephen S.
通讯作者：
Hecht, Stephen S.
影响因子：
3.7
作者：
Malin, Steven K.;Rynders, Corey A.;Weltman, Arthur
通讯作者：
Weltman, Arthur
吸烟引起的人类胰岛素抵抗的新颖和可逆机制。
影响因子：
7.7
作者：
Bergman BC;Perreault L;Hunerdosse D;Kerege A;Playdon M;Samek AM;Eckel RH
通讯作者：
Eckel RH
影响因子：
8.3
作者：
Mahmud, A;Feely, J
通讯作者：
Feely, J