Shuffled magnetization-prepared multicontrast rapid gradient-echo imaging.

Shuffled magnetization-prepared multicontrast rapid gradient-echo imaging.
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改组磁化准备的多对抗快速梯度回声成像。

DOI:
10.1002/mrm.26986
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发表时间:
2018-01
影响因子:
3.3
通讯作者:
Larson PEZ
Larson PEZ
中科院分区:
医学3区
文献类型:
--
作者:
Cao P;Zhu X;Tang S;Leynes A;Jakary A;Larson PEZ

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开发一种新的采集和重建方法,用于磁化准备的三维多对比度快速梯度回波成像,使用Hankel矩阵完成与压缩感知和并行成像相结合。在模拟和体内人体实验中,在7 T下实施随机k空间重排策略,用于三维反转恢复、T2/扩散制备和磁化传递成像。我们结合了压缩感知,基于总变分和时空低秩正则化,并行成像与像素汉克尔矩阵完成,允许重建数十个多对比度的三维图像从3或6分钟的扫描。仿真结果表明,该方法可以重建每个体素的信号恢复曲线,并对典型的在体信噪比具有16倍的加速度是鲁棒的。体内研究实现了4至24倍的加速反转恢复,T2/扩散准备,和磁化传递成像。此外,通过解析磁化制备后的逐像素信号恢复曲线来提高对比度。所提出的方法可以提高磁化准备MRI的采集效率,并且可以从单次扫描中恢复数十张多对比度三维图像。此外,它对噪声具有鲁棒性,适用于恢复多指数信号,并且不需要任何先前的模型参数知识。
To develop a novel acquisition and reconstruction method for magnetization-prepared 3-dimensional multicontrast rapid gradient-echo imaging, using Hankel matrix completion in combination with compressed sensing and parallel imaging. A random k-space shuffling strategy was implemented in simulation and in vivo human experiments at 7 T for 3-dimensional inversion recovery, T2/diffusion preparation, and magnetization transfer imaging. We combined compressed sensing, based on total variation and spatial-temporal low-rank regularizations, and parallel imaging with pixel-wise Hankel matrix completion, allowing the reconstruction of tens of multicontrast 3-dimensional images from 3- or 6-min scans. The simulation result showed that the proposed method can reconstruct signal-recovery curves in each voxel and was robust for typical in vivo signal-to-noise ratio with 16-times acceleration. In vivo studies achieved 4 to 24 times accelerations for inversion recovery, T2/diffusion preparation, and magnetization transfer imaging. Furthermore, the contrast was improved by resolving pixel-wise signal-recovery curves after magnetization preparation. The proposed method can improve acquisition efficiencies for magnetization-prepared MRI and tens of multicontrast 3-dimensional images could be recovered from a single scan. Furthermore, it was robust against noise, applicable for recovering multi-exponential signals, and did not require any previous knowledge of model parameters.
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