The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes.
The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes.
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DOI:
10.1093/nar/gkaa978
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发表时间:
2021-01-08
影响因子:
14.9
通讯作者:
Weber T
中科院分区:
文献类型:
--
作者:
Blin K;Shaw S;Kautsar SA;Medema MH;Weber T
Microorganisms produce natural products that are frequently used in the development of antibacterial, antiviral, and anticancer drugs, pesticides, herbicides, or fungicides. In recent years, genome mining has evolved into a prominent method to access this potential. antiSMASH is one of the most popular tools for this task. Here, we present version 3 of the antiSMASH database, providing a means to access and query precomputed antiSMASH-5.2-detected biosynthetic gene clusters from representative, publicly available, high-quality microbial genomes via an interactive graphical user interface. In version 3, the database contains 147 517 high quality BGC regions from 388 archaeal, 25 236 bacterial and 177 fungal genomes and is available at https://antismash-db.secondarymetabolites.org/. The antiSMASH database was updated to version 3, now containing 147 517 secondary/specialized metabolite biosynthetic gene clusters (BGCs) originating from 25 236 bacterial, 388 archaeal and 177 fungal genomes. The database provides interactive access to the detailed annotation of each BGC that was generated with the most recent version of antiSMASH (v5.2).
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影响因子:
9.5
作者:
Blin K;Kim HU;Medema MH;Weber T
通讯作者:
Weber T
影响因子:
14.8
作者:
Medema, Marnix H.;Fischbach, Michael A.
通讯作者:
Fischbach, Michael A.
影响因子:
14.9
作者:
Blin K;Medema MH;Kazempour D;Fischbach MA;Breitling R;Takano E;Weber T
通讯作者:
Weber T
影响因子:
14.9
作者:
Palaniappan, Krishnaveni;Chen, I-Min A.;Mouncey, Nigel J.
通讯作者:
Mouncey, Nigel J.
影响因子:
16.6
作者:
Jain C;Rodriguez-R LM;Phillippy AM;Konstantinidis KT;Aluru S
通讯作者:
Aluru S