Attention bias modification treatment: a meta-analysis toward the establishment of novel treatment for anxiety.

Attention bias modification treatment: a meta-analysis toward the establishment of novel treatment for anxiety.
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DOI:
10.1016/j.biopsych.2010.07.021
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发表时间:
2010-12-01
影响因子:
10.6
通讯作者:
Pine, Daniel S.
Pine, Daniel S.
中科院分区:
医学1区
文献类型:
--
作者:
Hakamata, Yuko;Lissek, Shmuel;Bar-Haim, Yair;Britton, Jennifer C.;Fox, Nathan A.;Leibenluft, Ellen;Ernst, Monique;Pine, Daniel S.

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注意偏倚矫正治疗(ABMT)是一种新兴的治疗焦虑症的方法。虽然最近的随机对照试验(rct)表明ABMT可以减轻焦虑,但治疗效果尚未得到定量总结。采用标准的元分析程序来总结ABMT对焦虑的影响。使用MEDLINE, 1995年1月至2010年2月,我们确定了比较ABMT对焦虑影响的随机对照试验,并使用Hedge 's d量化了效应量。12项研究符合纳入标准,包括来自10篇出版物的467名参与者。与对照训练相比,ABMT显著降低了焦虑,具有中等效果(d = 0.61, p < 0.001)。年龄和性别并不能缓和ABMT对焦虑的影响,而ABMT训练的一些特征却可以。ABMT有望成为一种治疗焦虑的新方法。需要更多的随机对照试验来充分评估这些发现重复和适用于患者的程度。未来的工作应该考虑ABMT在更广泛的焦虑障碍治疗领域的确切作用。
Attention Bias Modification Treatment (ABMT) is a newly-emerging promising treatment for anxiety disorders. While recent randomized control trials (RCTs) suggest that ABMT reduces anxiety, therapeutic effects have not been summarized quantitatively. Standard meta-analytic procedures were used to summarize the effect of ABMT on anxiety. Using MEDLINE, January 1995 to February 2010, we identified RCTs comparing the effects on anxiety of ABMT and quantified effect sizes using Hedge’s d. Twelve studies met inclusion criteria, including 467 participants from 10 publications. ABMT produced significantly greater reductions in anxiety than control training, with a medium effect (d = 0.61, p <.001). Age and gender did not moderate the effect of ABMT on anxiety, while several characteristics of the ABMT training did. ABMT shows promise as a novel treatment for anxiety. Additional RCTs are needed to fully evaluate the degree to which these findings replicate and apply to patients. Future work should consider the precise role for ABMT in the broader anxiety-disorder therapeutic armamentarium.
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