Neighborhood disadvantage, neighborhood safety and cardiometabolic risk factors in African Americans: biosocial associations in the Jackson Heart study.
Neighborhood disadvantage, neighborhood safety and cardiometabolic risk factors in African Americans: biosocial associations in the Jackson Heart study.
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DOI：
10.1371/journal.pone.0063254
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Albert MA
中科院分区：
文献类型：
--
作者：
Clark CR;Ommerborn MJ;Hickson DA;Grooms KN;Sims M;Taylor HA;Albert MA
我们研究了社区社会经济劣势、社区安全感和心脏代谢风险因素之间的关联，并根据非裔美国人的健康行为和社会经济地位（SES）进行了调整。研究参与者是杰克逊心脏研究基线检查（2000-2004 年）中的非糖尿病非裔美国人 (n = 3,909)。我们测量了八个危险因素：代谢综合征、其五个组成部分、胰岛素抵抗和心血管炎症。我们利用 2000 年美国人口普查数据评估了社区的社会经济劣势。我们通过调查评估了感知的社区安全、健康行为和社会经济地位。我们使用广义估计方程来估计与邻域效应的随机截距模型的关联。调整健康行为和社会经济地位后，社区社会经济劣势与女性代谢综合征相关（PR 1.13，95% CI 1.01，1.27）。缺乏安全感与女性血糖升高（OR 1.36，95% CI 1.03，1.80）和腰围（PR 1.06，95% CI 1.02，1.11）有关，也与血糖升高（PR 1.30，95% CI 1.02，1.66）和胰岛素抵抗（PR 1.25，95% CI 1.08， 1.46) 男性之间。应将社区社会经济劣势和安全感视为降低非裔美国人心脏代谢风险的干预目标。
We examined associations between neighborhood socioeconomic disadvantage, perceived neighborhood safety and cardiometabolic risk factors, adjusting for health behaviors and socioeconomic status (SES) among African Americans. Study participants were non-diabetic African Americans (n = 3,909) in the baseline examination (2000–2004) of the Jackson Heart Study. We measured eight risk factors: the metabolic syndrome, its five components, insulin resistance and cardiovascular inflammation. We assessed neighborhood socioeconomic disadvantage with US Census 2000 data. We assessed perceived neighborhood safety, health behaviors and SES via survey. We used generalized estimating equations to estimate associations with a random intercept model for neighborhood effects. After adjustment for health behaviors and SES, neighborhood socioeconomic disadvantage was associated with the metabolic syndrome in women (PR 1.13, 95% CI 1.01, 1.27). Lack of perceived safety was associated with elevated glucose (OR 1.36, 95% CI 1.03, 1.80) and waist circumference (PR 1.06, 95% CI 1.02, 1.11) among women, and with elevated glucose (PR 1.30, 95% CI 1.02, 1.66) and insulin resistance (PR 1.25, 95% CI 1.08, 1.46) among men. Neighborhood socioeconomic disadvantage and perceived safety should be considered as targets for intervention to reduce cardiometabolic risks among African Americans.
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影响因子：
16.2
作者：
Isomaa, B;Almgren, P;Groop, L
通讯作者：
Groop, L
影响因子：
5.6
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Clark, Cheryl R.;Kawachi, Ichiro;Berkman, Lisa F.
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Berkman, Lisa F.
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通讯作者：
Sarpong, Daniel F.
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16.2
作者：
McNeill, AM;Schmidt, MI;Heiss, G
通讯作者：
Heiss, G