Large-scale, closed-loop interrogation of neural circuits underlying cognition.
Large-scale, closed-loop interrogation of neural circuits underlying cognition.
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对认知基础的神经回路进行大规模的闭环式讯问。
DOI:
10.1016/j.tins.2022.10.003
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发表时间:
2022-12
影响因子:
15.9
通讯作者:
Gelinas JN
中科院分区:
文献类型:
--
作者:
Khodagholy D;Ferrero JJ;Park J;Zhao Z;Gelinas JN
Cognitive functions are increasingly understood to involve coordinated activity patterns between multiple brain regions, and their disruption by neuropsychiatric disorders is similarly complex. Closed-loop neurostimulation can directly modulate neural signals with temporal and spatial precision. How to leverage such an approach to effectively identify and target distributed neural networks implicated in mediating cognition remains unclear. We review current conceptual and technical advances in this area, proposing that devices that enable large-scale acquisition, integrated processing, and multi-region, arbitrary waveform stimulation will be critical for mechanistically-driven manipulation of cognitive processes in physiologic and pathologic brain networks.
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影响因子:
16.2
作者:
Fries P
通讯作者:
Fries P
影响因子:
16.6
作者:
Ezzyat Y;Wanda PA;Levy DF;Kadel A;Aka A;Pedisich I;Sperling MR;Sharan AD;Lega BC;Burks A;Gross RE;Inman CS;Jobst BC;Gorenstein MA;Davis KA;Worrell GA;Kucewicz MT;Stein JM;Gorniak R;Das SR;Rizzuto DS;Kahana MJ
通讯作者:
Kahana MJ
DOI:
10.1126/science.abf3119
发表时间:
2021-04-02
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Fernández-Ruiz A;Oliva A;Soula M;Rocha-Almeida F;Nagy GA;Martin-Vazquez G;Buzsáki G
通讯作者:
Buzsáki G
影响因子:
8.6
作者:
Benabid, AL;Benazzous, A;Pollak, P
通讯作者:
Pollak, P
影响因子:
56.9
作者:
Fuller, Elliot J.;Keene, Scott T.;Talin, A. Alec
通讯作者:
Talin, A. Alec