Incidence of multiple primary cancers in a cohort of women diagnosed with breast cancer in southeast England.

Incidence of multiple primary cancers in a cohort of women diagnosed with breast cancer in southeast England.
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DOI:
10.1054/bjoc.2000.1603
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发表时间:
2001-02-02
影响因子:
8.8
通讯作者:
Hodgson SV
Hodgson SV
中科院分区:
医学1区
文献类型:
--
作者:
Evans HS;Lewis CM;Robinson D;Bell CM;Møller H;Hodgson SV

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Among women in the Thames Cancer Registry database with a first breast cancer diagnosed between 1961–1995 observed numbers of subsequent cancers were compared with expected numbers and standardized incidence ratios were calculated. The occurrence of breast cancers subsequent to cancers at other sites was also examined. Women diagnosed with breast cancer before age 50 had significantly elevated risks for 9 cancer sites namely, oesophagus, stomach, lung, bone, connective tissue, breast, corpus uteri, ovary and myeloid leukaemia compared with 2 sites (corpus uteri and myeloid leukaemia) in women diagnosed at age 50 and above. Some of these associations are consistent with the effects of known inherited cancer susceptibility genes, shared environmental factors, or therapy. © 2001 Cancer Research Campaign http://www.bjcancer.com
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发表时间: 2000-05-01
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