Cross domain self-monitoring in anosognosia for memory loss in Alzheimer's disease.
Cross domain self-monitoring in anosognosia for memory loss in Alzheimer's disease.
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DOI：
10.1016/j.cortex.2018.01.019
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发表时间：
2018-04
期刊：
影响因子：
--
通讯作者：
Cosentino S
中科院分区：
文献类型：
--
作者：
Chapman S;Colvin LE;Vuorre M;Cocchini G;Metcalfe J;Huey ED;Cosentino S
记忆丧失的病感失认症是阿尔茨海默病（AD）的常见特征。最近的理论提出，病感失认症是一种全球水平的意识中断，可能反映了自我监控或局部意识的特定缺陷。虽然记忆丧失的病感失认症已被证明与记忆自我监控有关，但尚不清楚它是否与其他领域（即运动）的自我监控缺陷有关。目前的研究通过分析35名轻度至中度AD患者的病感失认症与记忆丧失、记忆监测和运动监测之间的关系来检验这个问题。在参与者完成测量记忆监测的元记忆任务和测量运动监测的计算机代理任务之前，通过临床访谈对病感失认进行评估。认知和心理测试包括记忆、执行功能和情绪。记忆监测与运动监测相关联；然而，病感失认症只与记忆监测有关，而与运动监测无关。认知和情绪与自我意识的不同程度相关。结果在意识的层次模型中进行解释，在该模型中，局部自我监控过程跨领域相关联，但似乎仅以特定于领域的方式促进全局水平的意识。
Anosognosia for memory loss is a common feature of Alzheimer’s disease (AD). Recent theories have proposed that anosognosia, a disruption in awareness at a global level, may reflect specific deficits in self-monitoring, or local awareness. Though anosognosia for memory loss has been shown to relate to memory self-monitoring, it is not clear if it relates to self-monitoring deficits in other domains (i.e., motor). The current study examined this question by analyzing the relationship between anosognosia for memory loss, memory monitoring, and motor monitoring in 35 individuals with mild to moderate AD. Anosognosia was assessed via clinical interview before participants completed a metamemory task to measure memory monitoring, and a computerized agency task to measure motor monitoring. Cognitive and psychological measures included memory, executive functions, and mood. Memory monitoring was associated with motor monitoring; however, anosognosia was associated only with memory monitoring, and not motor monitoring. Cognition and mood related differently to each measure of self-awareness. Results are interpreted within a hierarchical model of awareness in which local self-monitoring processes are associated across domain, but appear to only contribute to global levels awareness in a domain-specific fashion.
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影响因子：
2.1
作者：
Cotrell, V;Wild, K
通讯作者：
Wild, K
DOI：
10.1080/01688639008400980
发表时间：
1990-03-01
影响因子：
2.2
作者：
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通讯作者：
PIROZZOLO, FJ
影响因子：
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作者：
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通讯作者：
FEINBERG, I
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影响因子：
2.4
作者：
Cosentino, Stephanie;Metcalfe, Janet;Stern, Yaakov
通讯作者：
Stern, Yaakov
影响因子：
3.5
作者：
Cioffi MC;Cocchini G;Banissy MJ;Moore JW
通讯作者：
Moore JW