Multifunctional silica nanoparticles as a promising theranostic platform for biomedical applications
Multifunctional silica nanoparticles as a promising theranostic platform for biomedical applications
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多功能二氧化硅纳米颗粒作为生物医学应用的有前途的治疗诊断平台
DOI：
10.1039/c7qm00153c
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发表时间：
2017-06
影响因子：
7
通讯作者：
Yuejun Kang
中科院分区：
文献类型：
--
作者：
Zhigang Xu;Xiaoqian Ma;Yong-E Gao;Meili Hou;Peng Xue;Chang Ming Li;Yuejun Kang
诊疗一体化纳米平台是许多重大疾病诊断和治疗的重要工具，尤其是在癌症诊疗领域。在该领域有无数的纳米平台，比如聚合物胶束、脂质体以及无机纳米颗粒。
Theranostic nanoplatforms represent an important tool in the diagnosis and therapy of many major diseases, especially in the field of cancer theranostics, for which a myriad of nanoplatforms, such as polymeric micelles, liposomes and inorganic nanoparticles (NPs), have been designed and developed in recent decades. Among these nanoplatforms, silica NPs provide many advantages over other similar systems for therapeutics, bioimaging, bio-adhesives and many other biomedical applications. Therapeutic nanoplatforms based on mesoporous silica NPs (typically of pore size 2–50 nm) have been reviewed extensively. Herein, we provide an overview of recent advances in the development of theranostic nanoplatforms based on nonporous silica NPs within a size range of 1–200 nm for many critical biomedical applications, particularly stimuli-triggered drug delivery, precise cancer diagnosis as well as tissue bio-adhesive materials.
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DOI：
10.1039/b902195g
发表时间：
2009-05-28
期刊：
Chemical communications (Cambridge, England)
影响因子：
--
作者：
Ha SW;Camalier CE;Beck GR Jr;Lee JK
通讯作者：
Lee JK
影响因子：
5.6
作者：
Chen J;Densmore D;Ham TS;Keasling JD;Hillson NJ
通讯作者：
Hillson NJ
影响因子：
2.5
作者：
Y. Shan;Zhen Xiao;Y. Chuan;Hongli Li;Minglong Yuan;Zhen Li;Shixue Dou
通讯作者：
Y. Shan;Zhen Xiao;Y. Chuan;Hongli Li;Minglong Yuan;Zhen Li;Shixue Dou
影响因子：
17.1
作者：
Kumar R;Roy I;Ohulchanskky TY;Vathy LA;Bergey EJ;Sajjad M;Prasad PN
通讯作者：
Prasad PN
临床翻译的二氧化硅纳米颗粒作为以癌为标志性的探针进行图像引导的手术和干预措施。
DOI：
10.1039/c2ib20174g
发表时间：
2013-01
期刊：
Integrative biology : quantitative biosciences from nano to macro
影响因子：
--
作者：
Bradbury MS;Phillips E;Montero PH;Cheal SM;Stambuk H;Durack JC;Sofocleous CT;Meester RJ;Wiesner U;Patel S
通讯作者：
Patel S