Implantation and Establishment of Pregnancy in Human and Nonhuman Primates.

Implantation and Establishment of Pregnancy in Human and Nonhuman Primates.
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DOI:
10.1007/978-3-319-15856-3_10
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发表时间:
2015
影响因子:
--
通讯作者:
Fazleabas, Asgerally T.
Fazleabas, Asgerally T.
中科院分区:
生物学4区
文献类型:
--
作者:
Su, Ren-Wei;Fazleabas, Asgerally T.

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着床和怀孕的建立对于物种的繁殖至关重要,但仍然是人类和灵长类繁殖的限制步骤。成功着床需要在月经周期的特定时间窗口内有一个有能力的囊胚和一个接受性子宫内膜,以启动建立成功妊娠所需的双侧通信。本章提供了这些过程的概述,并讨论了与灵长类动物的胚泡着床和子宫蜕膜化相关的分子机制。
Implantation and the establishment of pregnancy are critical for the propagation of the species, but yet remain the limiting steps in human and primate reproduction. Successful implantation requires a competent blastocyst and a receptive endometrium during a specific window of time during the menstrual cycle to initiate the bilateral communication required for the establishment of a successful pregnancy. This chapter provides an overview of these processes and discusses the molecular mechanisms associated with implantation of the blastocyst and decidualization of the uterus in primates.
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