Cause of death in adults with intellectual disability in the United States.
Cause of death in adults with intellectual disability in the United States.
复制标题
美国智障成年人的死亡原因。
DOI：
10.1111/jir.12790
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发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
Turk MA
中科院分区：
文献类型：
--
作者：
Landes SD;Stevens JD;Turk MA
先前的研究报告称，智力残疾（ID）成年人的死因模式与普通人群中的成年人不同，但没有提供具体死因的比较分析。数据来自国家生命统计系统2005-2017年美国多死因死亡率文件。我们利用调整后的比值比来确定死亡证明上显示ID的成年人更常见的死亡原因（N = 22 512）比死亡证明未注明ID的成年人（N = 32 738 229），控制ID的严重程度。然后，我们研究了生物性别和种族之间的关联-死亡证明上显示，有身份证和没有身份证的成年人的主要死亡原因是心脏病。患有ID的成年人，无论残疾的严重程度如何，死于肺炎，流感/肺炎和窒息的风险都要高得多。轻度/中度ID的成年人也有较高的糖尿病死亡风险。死亡原因趋势的差异与生物学性别和种族有关。降低成人ID过早死亡率的努力应该注意一般人群中常见的死亡原因的风险因素，如心脏病和癌症，但也应该认识到所有成人ID中窒息死亡的风险增加，和糖尿病在成人中的轻度/需要进一步的研究来更好地了解决定肿瘤死亡率相对较低的因素和人口统计学差异在成人ID死亡原因中。
Prior studies report that adults with intellectual disability (ID) have cause of death patterns distinct from adults in the general population but do not provide comparative analysis by specific causes of death. Data are from the National Vital Statistics System 2005–2017 US Multiple Cause-of-Death Mortality files. We utilised adjusted odds ratios to identify causes of death that were more common for adults whose death certificate indicated ID (N = 22 512) than for adults whose death certificate did not indicate ID (N = 32 738 229), controlling for severity level of ID. We then examine the associations between biological sex and race-ethnicity and causes of death solely among adults with ID. The leading cause of death for adults with and without ID indicated on their death certificate was heart disease. Adults with ID, regardless of the severity of the disability, had substantially higher risk of death from pneumonitis, influenza/pneumonia and choking. Adults with mild/moderate ID also had higher risk of death from diabetes mellitus.Differences in cause of death trends were associated with biological sex and race-ethnicity. Efforts to reduce premature mortality for adults with ID should attend to risk factors for causes of death typical in the general population such as heart disease and cancer, but also should be cognisant of increased risk of death from choking among all adults with ID, and diabetes among adults with mild/moderate ID. Further research is needed to better understand the factors determining comparatively lower rates of death from neoplasms and demographic differences in causes of death among adults with ID.
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影响因子：
3.6
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