Diurnal intraocular pressure patterns are not repeatable in the short term in healthy individuals.
Diurnal intraocular pressure patterns are not repeatable in the short term in healthy individuals.
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DOI：
10.1016/j.ophtha.2010.01.044
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发表时间：
2010-09
期刊：
影响因子：
13.7
通讯作者：
Wisniewski SR
中科院分区：
文献类型：
--
作者：
Realini T;Weinreb RN;Wisniewski SR
评价非青光眼受试者眼内昼夜眼压（IOP）模式的短期可重复性。观察性队列研究。40例无青光眼的健康受试者。受试者于0800 - 2000进行12小时昼夜IOP评估，两次访视间隔一周。采用Goldmann压平眼压计测量眼压。进行分析以确定从第一次访视到第二次访视的个体昼夜IOP模式的关联强度。使用组内相关系数（ICC）分析访视之间每个时间点的IOP值的一致性和访视之间时间点之间IOP随时间的变化。昼夜IOP模式。每个时间点的IOP值访视间一致性通常为一般至良好，右眼的ICC范围为0.37至0.62，左眼为0.35至0.71。各时间点之间IOP变化随时间变化的访视间一致性均较差，通常低于预期值（仅偶然），右眼ICC范围为-0.25至0.15，左眼为-0.40至0.22。当通过Goldmann眼压计测量时，健康个体的眼睛没有表现出持续的和可再现的昼夜IOP模式。一天的IOP评估不能很好地表征昼夜IOP模式。
To evaluate the short-term repeatability of diurnal intraocular pressure (IOP) patterns in eyes of subjects without glaucoma. Observational cohort study. 40 healthy subjects without glaucoma. Subjects underwent 12-hour diurnal IOP assessment sessions from 0800 to 2000 on two visits one week apart. IOP was assessed by Goldmann applanation tonometry. An analysis was performed to determine the strength of association of individual diurnal IOP patterns from the first visit to the second visit. The intraclass correlation coefficient (ICC) was utilized to analyze both agreement of IOP values at each time point between visits and IOP change over time periods between time points between visits. Diurnal IOP patterns. Between-visit agreement of IOP values at each time point was generally fair to good, with ICCs ranging from 0.37 to 0.62 in right eyes and from 0.35 to 0.71 in left eyes. Between-visit agreement of IOP change over time periods between time points was uniformly poor and often below that expected by chance alone, with ICCs ranging from −0.25 to 0.15 in right eyes and from −0.40 to 0.22 in left eyes. Eyes of healthy individuals do not manifest a sustained and reproducible diurnal IOP pattern when measured by Goldmann tonometry. A single-day assessment of IOP poorly characterizes the diurnal IOP pattern.
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影响因子：
4.1
作者：
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