Prevention of Candida biofilm formation over polystyrene by plasma polymerization technique

Prevention of Candida biofilm formation over polystyrene by plasma polymerization technique
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通过等离子体聚合技术预防聚苯乙烯上念珠菌生物膜的形成

DOI:
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发表时间:
2020
期刊:
影响因子:
1.9
通讯作者:
J. S. Göçmen
J. S. Göçmen
中科院分区:
材料科学4区
文献类型:
--
作者:
Gizem Kaleli;Elvan Hortaç;Hatice Ferda Özgüzar;M. Mutlu;H. Mirza;A. Basustaoglu;J. S. Göçmen

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本工作研究了由低压射频等离子体系统使用丙烯酸、甲基丙烯酸2-羟乙酯和亚磷酸二乙酯(DEP)产生的等离子体聚合物膜的抗真菌效果。用30株生物膜阳性念珠菌对未修饰和血浆修饰的聚苯乙烯(PS)微孔板威尔斯孔进行检测。使用定量空斑测定方法从血液样品和两种对照菌株中分离。无论前体和等离子体参数如何,所有等离子体修饰的微孔板威尔斯孔的生物膜形成均受到抑制。当等离子体功率为90 W时,DEP修饰的PS对所有念珠菌的生物被膜形成均有抑制作用,其中以DEP修饰的PS的生物被膜抑制效果最显著。
This work investigates the antifungal effect of plasma polymer films produced by low-pressure RF-generated plasma system using acrylic acid, 2–hydroxyethyl methacrylate, and diethyl phosphite (DEP). Unmodified and plasma-modified polystyrene (PS) microplate wells were tested by 30 biofilm-positive Candida spp. isolated from blood samples and two control strains using a quantitative plaque assay method. Regardless of the precursors and plasma parameters, biofilm formation was inhibited for all plasma-modified microplate wells. The most significant anti-biofilm effect was observed on PS modified by DEP at 90 W plasma power with the inhibition of all Candida species’ biofilm formation.
DOI: 10.1016/j.colsurfb.2020.111177
发表时间: 2020-10-01
影响因子: 5.8
作者:
Dauben, Thomas J.;Dewald, Carolin;Jandt, Klaus D.
通讯作者: Jandt, Klaus D.
DOI: 10.1016/j.colsurfb.2016.05.049
发表时间: 2016-09-01
影响因子: 5.8
作者:
Luedecke, Claudia;Roth, Martin;Jandt, Klaus D.
通讯作者: Jandt, Klaus D.