An Approach to Neuroimaging Interpersonal Interactions in Mental Health Interventions.
An Approach to Neuroimaging Interpersonal Interactions in Mental Health Interventions.
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DOI：
10.1016/j.bpsc.2022.01.008
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发表时间：
2022-07
期刊：
影响因子：
--
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临床神经科学中的传统范式往往在生态有效性方面受到限制，这给临床环境中调节治疗和结果的机制提出了几个挑战。解决这些问题需要现实世界的神经成像技术，这些技术能够在自由流动的人际互动过程中连续收集数据，并允许进行代表它们发生的临床情况的实验设计。在这项工作中，我们开发了一种范式，对临床情况下发生的人与人之间的言语互动的主要组成部分进行了细分，并使用功能性近红外光谱来评估支撑临床医生-客户话语的大脑系统(n=30)。在临床互动中，人与人之间的跨脑神经耦合比日常生活中的语言交流要强得多，尤其是在前额叶(PFC)(例如，额下回)和顶下小叶(例如，缘上回)之间。有趣的是，临床任务显示，当参与者被要求默默地对另一个人的认知障碍进行推理时，整个PFC的活动都有广泛的增加，特别是在头端PFC(第10区)。这项工作展示了一种新的实验方法来研究通常发生在临床环境中的人际互动的神经基础，其发现支持了这样的观点，即特定的前额叶系统可能对培养心理健康至关重要。
Conventional paradigms in clinical neuroscience tend to be constrained in terms of ecological validity, raising several challenges to studying the mechanisms mediating treatments and outcomes in clinical settings. Addressing these issues requires real-world neuroimaging techniques that are capable of continuously collecting data during free-flowing interpersonal interactions and that allow for experimental designs which are representative of the clinical situations in which they occur. In this work, we developed a paradigm that fractionates the major components of the human-to-human verbal interactions occurring in clinical situations and used functional near-infrared spectroscopy to assess the brain systems underlying clinician-client discourse (n = 30). Cross-brain neural coupling between people was significantly greater during clinical interactions compared to everyday-life verbal communication, particularly between the prefrontal cortex (PFC) (e.g., inferior frontal gyrus) and inferior parietal lobule (e.g., supramarginal gyrus). Interestingly, the clinical tasks revealed extensive increases in activity across the PFC, especially in rostral PFC (area 10) during periods in which participants were required to silently reason about the dysfunctional cognitions of the other person. This work demonstrates a novel experimental approach to investigating the neural underpinnings of interpersonal interactions that typically occur in clinical settings, and its findings support the idea that particular prefrontal systems might be critical to cultivating mental health.
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影响因子：
3.7
作者：
Buhle, Jason T.;Silvers, Jennifer A.;Ochsner, Kevin N.
通讯作者：
Ochsner, Kevin N.
DOI：
10.1109/embc44109.2020.9175608
发表时间：
2020-07
期刊：
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
影响因子：
--
作者：
Anzolin A;Isenburg K;Grahl A;Toppi J;Yucel M;Ellingsen DM;Gerber J;Ciaramidaro A;Astolfi L;Kaptchuk TJ;Napadow V
通讯作者：
Napadow V
影响因子：
4.7
作者：
Crum J
通讯作者：
Crum J
影响因子：
5.7
作者：
Diekhof, Esther Kristina;Geier, Katharina;Gruber, Oliver
通讯作者：
Gruber, Oliver
影响因子：
2.6
作者：
Cipolotti, Lisa;Spano, Barbara;Bozzali, Marco
通讯作者：
Bozzali, Marco