ST proteins, a new family of plant tandem repeat proteins with a DUF2775 domain mainly found in Fabaceae and Asteraceae.
ST proteins, a new family of plant tandem repeat proteins with a DUF2775 domain mainly found in Fabaceae and Asteraceae.
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ST蛋白是一个新的植物串联重复蛋白质家族，其主要在Fabaceae和Asteraceae中发现的DUF2775结构域。
DOI：
10.1186/1471-2229-12-207
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发表时间：
2012-11-07
影响因子：
5.3
通讯作者：
Dopico B
中科院分区：
文献类型：
--
作者：
Albornos L;Martín I;Iglesias R;Jiménez T;Labrador E;Dopico B
许多具有串联重复序列的蛋白质已被描述，并根据重复序列的长度进行分类：i)短寡肽(从2到20个氨基酸)的重复序列，包括结构细胞壁蛋白和阿拉伯半乳糖蛋白。二)重复序列，长度从20到40个残基不等，包括具有良好三维结构的蛋白质，通常参与调节蛋白质之间的相互作用。(Iii)组成结构和功能独立单位的100个氨基酸的顺序较长的重复。在这里，我们分析了茎特异(ST)蛋白，这是一个具有未知功能的串联重复序列的蛋白质家族，最初在豆科中发现，以及它们与其他具有串联重复序列的蛋白质可能的相似性。ST蛋白序列仅存在于双子叶植物中，仅限于几个植物科，主要是豆科和菊科植物。ST的mRNAs主要积累在根部和生物相互作用下。大多数ST蛋白都有一个或几个功能未知的结构域(S)。所有推导出的ST蛋白都有一个信号肽，表明这些蛋白进入了分泌途径，成熟蛋白具有串联重复的寡肽，这些寡肽共享一个六肽(E/D)FEPRP，然后是4个部分保守的氨基酸，可以决定一个可能的N-糖基化信号，以及一个完全保守的酪氨酸。在系统发育树中，序列根据分类群分枝。尽管不同的STS可能在植物发育中扮演不同的角色，但可能参与了共生和非生物胁迫以及植物细胞的伸长。我们描述了一个新的蛋白质家族，称为ST，它的存在仅限于植物界，特别是一些双子叶植物家族。它们提供了20到40个氨基酸的串联重复序列，它们来自所描述的20到40个氨基酸串联重复蛋白和已知的具有重复序列的细胞壁蛋白，这些序列具有不同的特征(信号肽、DUF2775结构域、保守重复区域)。从所发现的特征中可以推断出在植物生理学中的几个假定作用。
Many proteins with tandem repeats in their sequence have been described and classified according to the length of the repeats: I) Repeats of short oligopeptides (from 2 to 20 amino acids), including structural cell wall proteins and arabinogalactan proteins. II) Repeats that range in length from 20 to 40 residues, including proteins with a well-established three-dimensional structure often involved in mediating protein-protein interactions. (III) Longer repeats in the order of 100 amino acids that constitute structurally and functionally independent units. Here we analyse ShooT specific (ST) proteins, a family of proteins with tandem repeats of unknown function that were first found in Leguminosae, and their possible similarities to other proteins with tandem repeats. ST protein sequences were only found in dicotyledonous plants, limited to several plant families, mainly the Fabaceae and the Asteraceae. ST mRNAs accumulate mainly in the roots and under biotic interactions. Most ST proteins have one or several Domain(s) of Unknown Function 2775 (DUF2775). All deduced ST proteins have a signal peptide, indicating that these proteins enter the secretory pathway, and the mature proteins have tandem repeat oligopeptides that share a hexapeptide (E/D)FEPRP followed by 4 partially conserved amino acids, which could determine a putative N-glycosylation signal, and a fully conserved tyrosine. In a phylogenetic tree, the sequences clade according to taxonomic group. A possible involvement in symbiosis and abiotic stress as well as in plant cell elongation is suggested, although different STs could play different roles in plant development. We describe a new family of proteins called ST whose presence is limited to the plant kingdom, specifically to a few families of dicotyledonous plants. They present 20 to 40 amino acid tandem repeat sequences with different characteristics (signal peptide, DUF2775 domain, conservative repeat regions) from the described group of 20 to 40 amino acid tandem repeat proteins and also from known cell wall proteins with repeat sequences. Several putative roles in plant physiology can be inferred from the characteristics found.
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影响因子：
7.2
作者：
CHEUNG, AY;MAY, B;WU, HM
通讯作者：
WU, HM
影响因子：
7.2
作者：
Floss, Daniela S.;Hause, Bettina;Walter, Michael H.
通讯作者：
Walter, Michael H.
影响因子：
5.1
作者：
DEVRIES, SC;HARMSEN, MC;WESSELS, JGH
通讯作者：
WESSELS, JGH
影响因子：
6.8
作者：
Groves, MR;Barford, D
通讯作者：
Barford, D
影响因子：
3.5
作者：
Fukuoka, Hiroyuki;Yamaguchi, Hirotaka;Ohyama, Akio
通讯作者：
Ohyama, Akio