Right dorsolateral prefrontal cortex is engaged during post-retrieval processing of both episodic and semantic information.
Right dorsolateral prefrontal cortex is engaged during post-retrieval processing of both episodic and semantic information.
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DOI：
10.1016/j.neuropsychologia.2009.04.010
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发表时间：
2009-10
期刊：
影响因子：
2.6
通讯作者：
Rugg MD
中科院分区：
文献类型：
--
作者：
Hayama HR;Rugg MD
当必须监测或评估检索尝试的结果时，需要进行检索后处理。功能神经成像研究表明，右侧背外侧前额叶皮质(DLPFC)在提取后加工中发挥作用。本研究使用功能磁共振成像来调查DLPFC中与提取相关的神经活动是否与监控提取尝试的情节内容特定相关。在研究过程中，受试者被提示对连续呈现的图片做出两种语义判断之一。一个研究阶段之后是来源记忆任务，受试者对未学习的图片做出新的反应，并表示对每一张已学习图片做出的语义判断。在一个单独的研究阶段之后是一个任务，在这个任务中，被研究的项目受到关于它们的语义属性的判断。这两项任务都要求在回答选择之前对检索到的信息进行评估，但只有来源记忆任务需要对检索到的情节信息进行评估。在这两个任务中，被研究的项目右侧DLPFC共同区域的活动比未被研究的项目的活动要大，而且这种影响的大小在不同的任务中没有差异。结合一项平行的事件相关电位研究的结果(H.R.Hayama等人，NeuroPenologia(2008)，46,1211-1223)，本研究结果表明，DLPFC与提取后加工的假设正确相关并不完全与监控或评估情节内容有关。相反，这些影响可能反映了与多个认知域的监控或决策相关的处理。
Post-retrieval processes are engaged when the outcome of a retrieval attempt must be monitored or evaluated. Functional neuroimaging studies have implicated right dorsolateral prefrontal cortex (DLPFC) as playing a role in post-retrieval processing. The present study used fMRI to investigate whether retrieval-related neural activity in DLPFC is associated specifically with monitoring the episodic content of a retrieval attempt. During study, subjects were cued to make one of two semantic judgments on serially presented pictures. One study phase was followed by a source memory task, in which subjects responded ‘new’ to unstudied pictures, and signaled the semantic judgment made on each studied picture. A separate study phase was followed by a task in which the studied items were subjected to a judgment about their semantic attributes. Both tasks required that retrieved information be evaluated prior to response selection, but only the source memory task required evaluation of retrieved episodic information. In both tasks, activity in a common region of right DLPFC was greater for studied than for unstudied items, and the magnitude of this effect did not differ between the tasks. Together with the results of a parallel event-related potential study (H.R. Hayama et al., Neuropsychologia (2008), 46, 1211–1223), the present findings indicate that putative right DLPFC correlates of post-retrieval processing are not associated exclusively with monitoring or evaluating episodic content. Rather, the effects likely reflect processing associated with monitoring or decision-making in multiple cognitive domains.
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影响因子：
16.2
作者：
Dobbins, IG;Foley, H;Wagner, AD
通讯作者：
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影响因子：
3.2
作者：
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通讯作者：
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作者：
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DOI：
10.1073/pnas.98.2.676
发表时间：
2001-01-16
影响因子：
11.1
作者：
Raichle, ME;MacLeod, AM;Shulman, GL
通讯作者：
Shulman, GL
DOI：
10.1196/annals.1440.011
发表时间：
2008-01-01
期刊：
YEAR IN COGNITIVE NEUROSCIENCE 2008
影响因子：
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作者：
Buckner, Randy L.;Andrews-Hanna, Jessica R.;Schacter, Daniel L.
通讯作者：
Schacter, Daniel L.