A visualization method for a wide range of rising temperature induced by high-intensity focused ultrasound using a tissue-mimicking phantom
A visualization method for a wide range of rising temperature induced by high-intensity focused ultrasound using a tissue-mimicking phantom
复制标题
使用模拟组织模型的高强度聚焦超声引起的大范围温度升高的可视化方法
DOI：
10.1080/02656736.2021.2012603
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发表时间：
2021
影响因子：
3.1
通讯作者：
Koseki Yoshihiko
中科院分区：
文献类型：
--
作者：
Takagi Ryo;Yoshinaka Kiyoshi;Washio Toshikatsu;Koseki Yoshihiko
目的高强度聚焦超声（HIFU）治疗需要事先评估HIFU换能器的输出。先前已经开发了一种使用微胶囊化热致变色液晶（MTLC）来评估HIFU暴露期间介质中的温度分布的方法。然而，商用MTLC的颜色编码温度范围约为10 °C，这不足以用于HIFU暴露的温度测量。我们创建了两层不同的颜色编码的温度范围的仿组织幻影，并开发了一种新的可视化方法，通过利用轴对称的压力分布的HIFU focus.MethodsA两层幻影具有两个灵敏度范围。将HIFU换能器设置为将焦点对准两层之间的边界。上下层的图像被翻转沿着两层之间的边界，使它们相互重叠，假设HIFU的压力分布是轴对称的。ResultsThe实验和模拟结果进行了比较，以评估的准确性的幻影温度测量。聚焦点周围温度和空间分布的实验时间分布与模拟结果吻合较好。然而，在轴向方向的HIFU focus.ConclusionUsers的准确性有改进的余地，可以在临床实践中应用我们提出的方法，及时评估治疗前的HIFU换能器的输出。
PurposeHigh-intensity focused ultrasound (HIFU) treatment requires prior evaluation of the HIFU transducer output. A method using micro-capsulated thermochromic liquid crystal (MTLC) to evaluate the temperature distribution in the media during HIFU exposure has been previously developed. However, the color-coded temperature range of commercial MTLC is approximately 10 °C, which is insufficient for temperature measurement for HIFU exposure. We created two layers of tissue-mimicking phantoms with different color-coded temperature ranges, and a new visualization method was developed by utilizing the axisymmetric pressure distribution of a HIFU focus.MethodsA two-layer phantom with two sensitivity ranges was created. The HIFU transducer was set to align the focal point to the boundary between the two layers. Images of the upper and lower layers were flipped along the boundary between the two layers such that they overlapped with each other, assuming the pressure distribution of HIFU to be axisymmetric.ResultsThe experimental and simulation results were compared to evaluate the accuracy of the phantom temperature measurement. The experimental time profile of the temperature and spatial distribution around the HIFU focus matched well with that of the simulation. However, there is room for improvement in the accuracy in the axial direction of HIFU focus.ConclusionUsers can apply our proposed method in clinical practice to promptly assess the output of the HIFU transducer before treatment.
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影响因子：
0.7
作者：
Andreeva, T. A.;Berkovich, A. E.;Lukin, A. Ya.
通讯作者：
Lukin, A. Ya.
使用时间反转向椎间盘传送聚焦超声波。
影响因子：
2.9
作者：
Qiao S
通讯作者：
Qiao S
使用 3D 测量系统可视化高强度聚焦超声焦点区域和近场周围的温度分布
影响因子：
1
作者：
T. Iwahashi;T. Tang;K. Matsui;K. Fujiwara;K. Itani;K. Yoshinaka;T. Azuma;S. Takagi;I. Sakuma
通讯作者：
I. Sakuma
影响因子：
19.7
作者：
Huang Y;Alkins R;Schwartz ML;Hynynen K
通讯作者：
Hynynen K
影响因子：
6.6
作者：
Bass, Roman;Fleshner, Neil;Klotz, Laurence
通讯作者：
Klotz, Laurence