Hippocampal dentation: Structural variation and its association with episodic memory in healthy adults.

Hippocampal dentation: Structural variation and its association with episodic memory in healthy adults.
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DOI:
10.1016/j.neuropsychologia.2017.04.036
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发表时间:
2017-07-01
期刊:
影响因子:
2.6
通讯作者:
Ver Hoef L
Ver Hoef L
中科院分区:
心理学3区
文献类型:
--
作者:
Fleming Beattie J;Martin RC;Kana RK;Deshpande H;Lee S;Curé J;Ver Hoef L

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While the hippocampus has long been identified as a structure integral to memory, the relationship between morphology and function has yet to be fully explained. We present an analysis of hippocampal dentation, a morphological feature previously unexplored in regard to its relationship with episodic memory. “Hippocampal dentation” in this case refers to surface convolutions, primarily present in the CA1/subiculum on the inferior aspect of the hippocampus. Hippocampal dentation was visualized using ultra-high resolution structural MRI and evaluated using a novel visual rating scale. The degree of hippocampal dentation was found to vary considerably across individuals, and was positively associated with verbal memory recall and visual memory recognition in a sample of 22 healthy adults. This study is the first to characterize the variation in hippocampal dentation in a healthy cohort and to demonstrate its association with aspects of episodic memory.
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