Nanoscale Bioreceptor Layers Comprising Carboxylated Polythiophene for Organic Electrochemical Transistor-Based Biosensors
Nanoscale Bioreceptor Layers Comprising Carboxylated Polythiophene for Organic Electrochemical Transistor-Based Biosensors
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用于基于有机电化学晶体管的生物传感器的包含羧化聚噻吩的纳米级生物受体层
DOI：
10.1021/acsanm.1c02949
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发表时间：
2021
影响因子：
5.9
通讯作者：
Katz, Howard E.
中科院分区：
文献类型：
--
作者：
Song, Yunjia;Lamberty, Zachary D.;Liang, Junhao;Aller Pellitero, Miguel;Wagner, Justine S.;Jumai’an, Eugenie;Bevan, Michael A.;Frechette, Joelle;Arroyo-Currás, Netzahualcóyotl;Katz, Howard E.
We investigated the carboxylated conjugated polymer poly 3-(3-carboxypropyl)thiophene-2,5-diyl as a nanosized (200–350 nm) biomolecule receptor layer on the channel of organic electrochemical transistor (OECT) devices. Myelin basic protein, SARS-CoV-2 spike glycoprotein S1, and their antibodies (10 nm size scale) were alternately used in the attached molecule form as receptors and analytes. Sub-ng detection in buffer was observed, and response to S1 was also obtained in clinical serum. Changes in threshold voltage and current output from OECT transfer curves and measurements of open circuit potential between receptor layers and a reference electrode provided complementary responses and insight into the response mechanisms, guiding further development of electrochemical field-effect and voltammetric protein sensors based on polymeric active layers with nanoscale functionality.
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影响因子：
29.4
作者：
Khan, Hadayat Ullah;Roberts, Mark E.;Bao, Zhenan
通讯作者：
Bao, Zhenan
影响因子：
1.5
作者：
Pawlowski, Piotr H.
通讯作者：
Pawlowski, Piotr H.
DOI：
10.1073/pnas.0405665101
发表时间：
2004-09-14
影响因子：
11.1
作者：
Hu, YF;Doudevski, I;Israelachvili, J
通讯作者：
Israelachvili, J
与水介质中的非极性表面相比，羧酸-功能化共轭聚合物可减少电子漂移并增强远程门的质子灵敏度
影响因子：
6.2
作者：
Jang, Hyun‐June;Wagner, Justine;Song, Yunjia;Lee, Taein;Katz, Howard E.
通讯作者：
Katz, Howard E.
DOI：
10.3390/ma7096843
发表时间：
2014-09-22
期刊：
Materials (Basel, Switzerland)
影响因子：
--
作者：
Minamiki T;Minami T;Kurita R;Niwa O;Wakida SI;Fukuda K;Kumaki D;Tokito S
通讯作者：
Tokito S