Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES).
Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES).
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DOI：
10.1093/ije/dyv072
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发表时间：
2015-08
影响因子：
7.7
通讯作者：
Davey Smith G
中科院分区：
文献类型：
--
作者：
Relton CL;Gaunt T;McArdle W;Ho K;Duggirala A;Shihab H;Woodward G;Lyttleton O;Evans DM;Reik W;Paul YL;Ficz G;Ozanne SE;Wipat A;Flanagan K;Lister A;Heijmans BT;Ring SM;Davey Smith G
ARIES是一个基于人群的DNA甲基化数据资源，可供研究界访问，其建立的目的是提高我们对表观遗传变异的决定因素和后果的理解，特别是DNA甲基化在健康和发展中的作用。为此，ARIES分析了从大约1000对母子对中选择的样本的全基因组DNA甲基化，在儿童的三个时间点和母亲的两个时间点。ARIES还分析了广泛的胎儿和成人组织供参考，以比较脐带血和外周血DNA甲基化模式。已经建立了一个门户网站，允许使用定制的数据整合系统（ARIES-Explorer），在基因功能许多方面的其他公开数据的背景下，公开浏览ARIES DNA甲基化总数据。
ARIES is a population-based resource of DNA methylation data accessible by the research community, established with the aim of improving our understanding of the determinants and consequences of epigenetic variation, in particular the role of DNA methylation in health and development. To this end, ARIES has profiled genomewide DNA methylation on samples selected from approximately 1000 mother-child pairs at three time points in children and two time points in their mothers. ARIES has also profiled a wide range of fetal and adult tissues for reference purposes, with which to compare cord blood and peripheral blood DNA methylation patterns. A web portal has been constructed to allow openly accessible browsing of aggregate ARIES DNA methylation data in the context of other publicly available data on many aspects of gene function, using a custom-built data integration system (ARIES-Explorer).Population-based DNA methylation profiling
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影响因子：
12.3
作者：
Jaffe AE;Irizarry RA
通讯作者：
Irizarry RA
从流行病学出生队列中绘制因果推断的方法：评论。
影响因子：
2.5
作者：
Richmond, Rebecca C.;Al-Amin, Aleef;Smith, George Davey;Relton, Caroline L.
通讯作者：
Relton, Caroline L.
影响因子：
3.8
作者：
Kirkbride JB;Susser E;Kundakovic M;Kresovich JK;Davey Smith G;Relton CL
通讯作者：
Relton CL
影响因子：
16.6
作者：
Taylor, Peter N.;Porcu, Eleonora;Chew, Shelby;Campbell, Purdey J.;Traglia, Michela;Brown, Suzanne J.;Mullin, Benjamin H.;Shihab, Hashem A.;Min, Josine;Walter, Klaudia;Memari, Yasin;Huang, Jie;Barnes, Michael R.;Beilby, John P.;Charoen, Pimphen;Danecek, Petr;Dudbridge, Frank;Forgetta, Vincenzo;Greenwood, Celia;Grundberg, Elin;Johnson, Andrew D.;Hui, Jennie;Lim, Ee M.;McCarthy, Shane;Muddyman, Dawn;Panicker, Vijay;Perry, John R. B.;Bell, Jordana T.;Yuan, Wei;Relton, Caroline;Gaunt, Tom;Schlessinger, David;Abecasis, Goncalo;Cucca, Francesco;Surdulescu, Gabriela L.;Woltersdorf, Wolfram;Zeggini, Eleftheria;Zheng, Hou-Feng;Toniolo, Daniela;Dayan, Colin M.;Naitza, Silvia;Walsh, John P.;Spector, Tim;Smith, George Davey;Durbin, Richard;Richards, J. Brent;Sanna, Serena;Soranzo, Nicole;Timpson, Nicholas J.;Wilson, Scott G.
通讯作者：
Wilson, Scott G.
影响因子：
5.8
作者：
Aryee, Martin J.;Jaffe, Andrew E.;Irizarry, Rafael A.
通讯作者：
Irizarry, Rafael A.