Prevalence of gestational diabetes mellitus in mainland China: A systematic review and meta-analysis.

Prevalence of gestational diabetes mellitus in mainland China: A systematic review and meta-analysis.
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DOI:
10.1111/jdi.12854
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发表时间:
2019-01
影响因子:
3.2
通讯作者:
Yuan J
Yuan J
中科院分区:
医学3区
文献类型:
--
作者:
Gao C;Sun X;Lu L;Liu F;Yuan J

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患有妊娠期糖尿病(GDM)的孕妇有更高的不良妊娠结局风险。本研究的目的是根据国际糖尿病协会和妊娠研究小组的标准,估计大陆中国地区妊娠期糖尿病的合并患病率。我们通过检索英文和中文文献数据库进行了系统的综述。采用随机效应模型对大陆地区妊娠期糖尿病的患病率进行统计分析,中国。进行了亚组分析和敏感性分析以解决异质性问题。采用Egger‘s检验评价发表偏倚。共有25篇论文被纳入Meta-分析,涉及79,064名中国参与者。大陆地区妊娠期糖尿病的总发病率为14.8%(95%可信区间为12.8-16.7%)。亚组分析显示,年龄、体重、糖尿病家族史可显著增加妊娠期糖尿病的发病率。据我们所知,这项系统性综述是第一次根据国际糖尿病和妊娠研究小组的标准估计大陆中国妇女妊娠期糖尿病的合并患病率。我们系统回顾的结果显示,中国在内地的妊娠期糖尿病患病率很高,这表明这个国家可能是世界上妊娠期糖尿病患者最多的国家。
Pregnant women with gestational diabetes mellitus (GDM) are at a higher risk of adverse pregnancy outcomes. The aim of the present study was to estimate the pooled prevalence of GDM in mainland China according to International Association of Diabetes and Pregnancy Study Groups criteria. We carried out a systematic review by searching both English and Chinese literature databases. Random effects models were used to summarize the prevalence of GDM in mainland China. Subgroup and sensitivity analyses were carried out to address heterogeneity. Publication bias was evaluated using Egger's test. A total of 25 papers were included in the meta‐analysis, involving 79,064 Chinese participants. The total incidence of GDM in mainland China was 14.8% (95% confidence interval 12.8–16.7%). Subgroup analysis showed that the age, bodyweight and family history of diabetes mellitus could significantly increase the incidence of GDM. To the best of our knowledge, this systematic review is the first to estimate the pooled prevalence of GDM among women in mainland China according to International Association of Diabetes and Pregnancy Study Groups criteria. The results of our systematic review suggest a high prevalence of GDM in mainland China, indicating that this country might have the largest number of GDM patients worldwide.
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