Decreased serum vitamin D levels in early spontaneous pregnancy loss.
Decreased serum vitamin D levels in early spontaneous pregnancy loss.
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早期自然妊娠流产时血清维生素 D 水平降低
DOI:
10.1038/ejcn.2016.83
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发表时间:
2016-09
影响因子:
4.7
通讯作者:
中科院分区:
文献类型:
--
作者:
Results:By pregnancy/non-gravid, normal pregnant women had higher 25 (OH) D (49.32 μg/l) and CYP27B1 (82.00 pg/ml) than PL women (34.49 μg/l and 37.87 pg/ml, both P< 0.01); the non-gravid women with a successful pregnancy history also had higher 25 (OH) D (39.56 μg/l) and CYP27B1 (39.04 pg/ml) than women with PL history (12.30 μg/l and 12.35 pg/ml, both P< 0.01). The 96.7% of non-gravid women with PL history and 43.3% of PL women had serum 25 (OH) D concentrations below 30 μg/l. There was a strong association between low vitamin D levels and PL (odds ratio 1.71; 95% confidence interval: 1.2–2.4, P< 0.001). The regression analyses showed that PL was significantly inversely correlated with 25 (OH) D (P< 0.01) and CYP27B1 levels (P< 0.01).Conclusions:Vitamin D deficiency associated with PL in the first trimester of pregnancy. Decreased serum vitamin D levels among childbearing aged women with the failed clinical pregnancies history may predispose to increased risk for PL.
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DOI:
10.1016/j.jsbmb.2006.12.078
发表时间:
2007-03-01
影响因子:
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作者:
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通讯作者:
Adams, John S.