Understanding the impact of sex and gender in Alzheimer's disease: A call to action.
Understanding the impact of sex and gender in Alzheimer's disease: A call to action.
复制标题
了解性别和性别对阿尔茨海默氏病的影响：行动呼吁。
DOI：
10.1016/j.jalz.2018.04.008
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发表时间：
2018-09
期刊：
影响因子：
--
通讯作者：
Mielke MM
中科院分区：
文献类型：
--
作者：
Nebel RA;Aggarwal NT;Barnes LL;Gallagher A;Goldstein JM;Kantarci K;Mallampalli MP;Mormino EC;Scott L;Yu WH;Maki PM;Mielke MM
精确医学方法和途径促进了我们对阿尔茨海默病(AD)痴呆的临床表现、发展、进展和管理的理解。然而，性和性别尚未充分纳入其中许多办法。妇女健康协会关于阿尔茨海默病的跨学科研究网络由一个由科学家和临床医生组成的专家小组组成，审查了与阿尔茨海默病性别和性别差异有关的正在进行的和已发表的研究。目前的审查是该网络努力的结果，目的是：(1)突出AD领域关于性别和性别差异的最新科学状况；(2)解决在评估性别和性别差异方面的知识差距；(3)讨论值得进一步研究的12个优先领域。性别和性别的排除阻碍了在整个临床范围内发现、治疗和护理AD的更快进展。对这些差异的更多关注将改善两性的结果。
Precision medicine methodologies and approaches have advanced our understanding of the clinical presentation, development, progression, and management of Alzheimer’s disease (AD) dementia. However, sex and gender have not yet been adequately integrated into many of these approaches. The Society for Women’s Health Research Interdisciplinary Network on AD, comprised of an expert panel of scientists and clinicians, reviewed ongoing and published research related to sex and gender differences in AD. The current review is a result of this Network’s efforts and aims to: (1) highlight the current state-of-the-science in the AD field on sex and gender differences; (2) address knowledge gaps in assessing sex and gender differences; and (3) discuss 12 priority areas that merit further research. The exclusion of sex and gender has impeded faster advancement in the detection, treatment, and care of AD across the clinical spectrum. Greater attention to these differences will improve outcomes for both sexes.
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影响因子：
4.2
作者：
Beydoun MA;Boueiz A;Abougergi MS;Kitner-Triolo MH;Beydoun HA;Resnick SM;O'Brien R;Zonderman AB
通讯作者：
Zonderman AB
影响因子：
9.8
作者：
Aukes, Annet M.;Wessel, Ineke;Zeeman, Gerda G.
通讯作者：
Zeeman, Gerda G.
影响因子：
3.5
作者：
Carter, Christine L.;Resnick, Eileen M.;Kalbarczyk, Anna
通讯作者：
Kalbarczyk, Anna
影响因子：
9.9
作者：
Barnes, LL;Wilson, RS;Bennett, DA
通讯作者：
Bennett, DA
影响因子：
6.3
作者：
Beydoun, May A.;Beydoun, Hind A.;Zonderman, Alan B.
通讯作者：
Zonderman, Alan B.