Antibiotic prescribing patterns in Emergency Department at Regional Hospital in South Africa.

Antibiotic prescribing patterns in Emergency Department at Regional Hospital in South Africa.
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DOI:
10.4314/ahs.v21i4.19
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发表时间:
2021-12
影响因子:
1
通讯作者:
Parag N
Parag N
中科院分区:
医学4区
文献类型:
--
作者:
Almansoori N;Parag N

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抗生素耐药性是一个主要的公共卫生问题。急诊科(艾德)是社区的大门,经常开抗生素。然而,关于非洲抗生素处方做法的数据很少。描述艾德中抗生素的使用以及处方依从国家指南的水平。ED中抗生素实践的回顾性观察研究。纳入了研究期间到艾德就诊并接受抗微生物药物处方的所有患者。使用人口统计学、工作诊断、抗菌药物处方、剂量、给药途径和处方者水平数据提供这些参数的描述性统计量。我们确定了195(13.4%)例患者接受抗微生物治疗的1454图表审查。平均年龄为34.8岁,男性居多。确定的最常见适应症是脓肿,37例(30.8%)患者,在一般手术条件下,抗菌药物处方率最高,为54.3%。此外,复方阿莫西林是最常见的处方抗菌药物(72.15%)。我们发现联合治疗在艾德中并不常见,大多数患者接受单一抗菌药物治疗(87.18%)。抗菌药物处方的适当性为46.2%,无统计学意义(P = 0.654)。最常见的处方抗生素是阿莫西林,最常见的适应症是脓肿。结果发现,与发达国家进行的研究相比,抗生素处方的适当性是可以接受的。然而,在其他医院部门的进一步研究将增加研究,以确定作为一个机构,而不仅仅是急诊科的依从性,因为抗菌素耐药性是一个主要的全球医疗保健问题,并影响整个护理途径的患者护理。
Antibiotic resistance is a major public health concern. The Emergency department (ED) is the community gate for healthcare where antibiotics are often prescribed. However, there is a paucity of data regarding antibiotic prescription practices in Africa. To describe the use of antibiotics in an ED and level of prescribing adherence to national guidelines. Retrospective observational study of antibiotic practice in ED. All patients who presented to ED during the study period and were prescribed an anti-microbial agent were included. Data on demographics, working diagnosis, anti-microbial prescribed, dose, route and prescriber level were used to provide descriptive statistics of these parameters. We identified 195 (13.4%) patients who received anti-microbial therapy among 1454 charts reviewed. The mean age was 34.8 with male predominance. The most common indication identified was abscess in 37 (30.8%) patients and in general surgical conditions had the highest rate of antimicrobials prescribed at 54.3%. In addition, co-amoxiclav was the most commonly prescribed anti-microbial (72.15%). We found that combination therapy was not common practice in ED, with majority of the patients having received single anti-microbial therapy (87.18%). The appropriateness of antimicrobial prescriptions was (46.2%) and not statistically significant (P = 0.654). The most commonly prescribed anti-microbial was co amoxiclav and the most common indication was abscess. It was found that antibiotic prescription appropriateness was acceptable when compared to studies conducted in developed countries. However, further research within other hospital departments will add to the study to determine the adherence as an institution rather than the Emergency department alone, as antimicrobial resistance is a major global healthcare problem and impacts patient care throughout the care pathway.
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