Recent advances in cancer immunotherapy.
Recent advances in cancer immunotherapy.
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DOI：
10.1007/s12672-021-00422-9
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发表时间：
2021-08-18
影响因子：
2.2
通讯作者：
Shi Y
中科院分区：
文献类型：
--
作者：
Sun Q;Melino G;Amelio I;Jiang J;Wang Y;Shi Y
Cancer immunotherapy represents a major advance in the cure of cancer following the dramatic advancements in the development and refinement of chemotherapies and radiotherapies. In the recent decades, together with the development of early diagnostic techniques, immunotherapy has significantly contributed to improving the survival of cancer patients. The immune-checkpoint blockade agents have been proven effective in a significant fraction of standard therapy refractory patients. Importantly, recent advances are providing alternative immunotherapeutic tools that could help overcome their limitations. In this mini review, we provide an overview on the main steps of the discovery of classic immune-checkpoint blockade agents and summarise the most recent development of novel immunotherapeutic strategies, such as tumour antigens, bispecific antibodies and TCR-engineered T cells.
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DOI：
10.1073/pnas.1808314115
发表时间：
2018-11-13
影响因子：
11.1
作者：
Amelio I;Mancini M;Petrova V;Cairns RA;Vikhreva P;Nicolai S;Marini A;Antonov AA;Le Quesne J;Baena Acevedo JD;Dudek K;Sozzi G;Pastorino U;Knight RA;Mak TW;Melino G
通讯作者：
Melino G
影响因子：
4.3
作者：
Bellomaria, Alessia;Barbato, Gaetano;Melino, Sonia
通讯作者：
Melino, Sonia
影响因子：
3
作者：
Del Moral-Morales, Aylin;Carlos Gonzalez-Orozco, Juan;Camacho-Arroyo, Ignacio
通讯作者：
Camacho-Arroyo, Ignacio
DOI：
10.1038/nrc.2016.97
发表时间：
2016-08-23
期刊：
Nature reviews. Cancer
影响因子：
--
作者：
Fesnak AD;June CH;Levine BL
通讯作者：
Levine BL
影响因子：
5.5
作者：
Celardo I;Melino G;Amelio I
通讯作者：
Amelio I