Polarized release of enveloped viruses in the embryonic chick heart: demonstration of epithelial polarity in the presumptive myocardium.
Polarized release of enveloped viruses in the embryonic chick heart: demonstration of epithelial polarity in the presumptive myocardium.
复制标题
胚胎鸡心脏中包膜病毒的极化释放:假定心肌中上皮极性的证明。
DOI:
10.1016/0012-1606(90)90111-u
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发表时间:
1990
影响因子:
2.7
通讯作者:
Fischman,DA
中科院分区:
文献类型:
--
作者:
Peng,I;Dennis,JE;Rodriguez-Boulan,E;Fischman,DA
The presumptive myocardium of the embryonic vertebrate heart is composed of cells which exhibit the morphology of a cuboidal epithelium. To examine the functional polarity of these developing myocytes, embryonic chick hearts (Hamburger-Hamilton stages 10–13) were infected with either influenza virus (FLU) or vesicular stomatitis virus (VSV). These viruses have been shown to sort vectorially to either apical (FLU) or basolateral (VSV) membrane surfaces in monolayers of polarized kidney (MDCK) cells. Our results demonstrate that these viruses bud with comparable polarity from differentiating myocytes. However, there appear to be stage-dependent differences in the polarized budding of the two viruses: restricted basolateral release of VSV is present before or shortly after the formation of the heart tube, whereas polarized budding of FLU is established later in development. These results are discussed in terms of plasma membrane organization during the early stages of cardiac development.
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影响因子:
56.9
作者:
RODRIGUEZBOULAN, E;NELSON, WJ
通讯作者:
NELSON, WJ
DOI:
10.1159/000145781
发表时间:
1983
期刊:
Acta anatomica
影响因子:
--
作者:
J. Icardo;J. Ojeda;J. Hurlé
通讯作者:
J. Hurlé
影响因子:
7.8
作者:
Rodriguez-Boulan, E;Paskiet, K T;Sabatini, D D
通讯作者:
Sabatini, D D
DOI:
10.1083/jcb.104.4.905
发表时间:
1987-04
期刊:
The Journal of cell biology
影响因子:
--
作者:
Vega-Salas DE;Salas PJ;Gundersen D;Rodriguez-Boulan E
通讯作者:
Rodriguez-Boulan E
DOI:
--
发表时间:
1969
期刊:
The Anatomical Record
影响因子:
--
作者:
D. E. Kelly
通讯作者:
D. E. Kelly