Molecular correlates of spontaneous activity in non-human primates.

Molecular correlates of spontaneous activity in non-human primates.
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DOI:
10.1007/s00702-010-0483-7
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发表时间:
2010-12
影响因子:
3.3
通讯作者:
Greenough, William
Greenough, William
中科院分区:
医学3区
文献类型:
--
作者:
Mitchell, Amanda C.;Aldridge, Georgina;Kohler, Shawn;Stanton, Greg;Sullivan, Elinor;Garbett, Krassimira;Faludi, Gabor;Mirnics, Karoly;Cameron, Judy L.;Greenough, William

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在我们的猴子模型中,皮质ARC和BDNF的表达与自发性体力活动密切相关。ARC和BDNF的表达与血清CRP水平呈负相关,提示CRP可能是脑弹性的外周标志物。
In our monkey model, cortical ARC and BDNF expressions were strongly correlated with spontaneous physical activity. The expressions of ARC and BDNF were inversely correlated with serum CRP levels, suggesting that CRP could be a putative peripheral marker of brain resiliency.
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