Fast volumetric ultrasound facilitates high-resolution 3D mapping of tissue compartments.

Fast volumetric ultrasound facilitates high-resolution 3D mapping of tissue compartments.
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DOI:
10.1126/sciadv.adg8176
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发表时间:
2023-06-02
期刊:
影响因子:
13.6
通讯作者:
Ferrara, Katherine W.
Ferrara, Katherine W.
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Park, Eun-Yeong;Cai, Xiran;Foiret, Josquin;Bendjador, Hanna;Hyun, Dongwoon;Fite, Brett Z.;Wodnicki, Robert;Dahl, Jeremy J.;Boutin, Robert D.;Ferrara, Katherine W.

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Volumetric ultrasound imaging has the potential for operator-independent acquisition and enhanced field of view. Panoramic acquisition has many applications across ultrasound; spanning musculoskeletal, liver, breast, and pediatric imaging; and image-guided therapy. Challenges in high-resolution human imaging, such as subtle motion and the presence of bone or gas, have limited such acquisition. These issues can be addressed with a large transducer aperture and fast acquisition and processing. Programmable, ultrafast ultrasound scanners with a high channel count provide an unprecedented opportunity to optimize volumetric acquisition. In this work, we implement nonlinear processing and develop distributed beamformation to achieve fast acquisition over a 47-centimeter aperture. As a result, we achieve a 50-micrometer −6-decibel point spread function at 5 megahertz and resolve in-plane targets. A large volume scan of a human limb is completed in a few seconds, and in a 2-millimeter dorsal vein, the image intensity difference between the vessel center and surrounding tissue was ~50 decibels, facilitating three-dimensional reconstruction of the vasculature. Human-scale volumetric ultrasound imaging is accomplished in seconds using a large transducer aperture and distributed processing.
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