Structural and resting state functional connectivity beyond the cortex.

Structural and resting state functional connectivity beyond the cortex.
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DOI:
10.1016/j.neuroimage.2021.118379
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发表时间:
2021-10-15
期刊:
影响因子:
5.7
通讯作者:
Barry RL
Barry RL
中科院分区:
医学1区
文献类型:
--
作者:
Harrison OK;Guell X;Klein-Flügge MC;Barry RL

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绘制中枢神经系统的结构和功能连接图已成为神经成像研究中的一个关键领域。虽然已经使用动物模型探索了整个大脑的详细网络结构,但到目前为止,人类的非侵入性神经成像一直以皮质研究为主。在皮质之外,皮质下核团传统上较难接触到,因为它们较小,距离射频线圈更远。然而,主要的神经成像发展现在提供了更好的信号和研究这些结构所需的分辨率。在这里,我们将概述杏仁核、脑干、小脑、脊髓和大脑其他部分之间的联系。虽然他们的成像和分析仍然存在局限性,但我们也提供了一些建议和考虑,以绘制大脑皮质以外的连接。
Mapping the structural and functional connectivity of the central nervous system has become a key area within neuroimaging research. While detailed network structures across the entire brain have been probed using animal models, non-invasive neuroimaging in humans has thus far been dominated by cortical investigations. Beyond the cortex, subcortical nuclei have traditionally been less accessible due to their smaller size and greater distance from radio frequency coils. However, major neuroimaging developments now provide improved signal and the resolution required to study these structures. Here, we present an overview of the connectivity between the amygdala, brainstem, cerebellum, spinal cord and the rest of the brain. While limitations to their imaging and analyses remain, we also provide some recommendations and considerations for mapping brain connectivity beyond the cortex.
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发表时间: 2013-01-21
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