Investigating the Effects of COVID-19 Quarantine in Migraine: An Observational Cross-Sectional Study From the Italian National Headache Registry (RICe).
Investigating the Effects of COVID-19 Quarantine in Migraine: An Observational Cross-Sectional Study From the Italian National Headache Registry (RICe).
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DOI：
10.3389/fneur.2020.597881
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发表时间：
2020
影响因子：
3.4
通讯作者：
de Tommaso M
中科院分区：
文献类型：
--
作者：
Delussi M;Gentile E;Coppola G;Prudenzano AMP;Rainero I;Sances G;Abagnale C;Caponnetto V;De Cesaris F;Frattale I;Guaschino E;Marcinnò A;Ornello R;Pistoia F;Putortì A;Roca ME;Roveta F;Lupi C;Trojano M;Pierelli F;Geppetti P;Sacco S;de Tommaso M
背景资料：此前在SARS和埃博拉大流行期间的研究表明，隔离与几种负面的心理影响有关，如创伤后应激症状、困惑和愤怒。这些条件可能会影响许多疾病的过程，包括偏头痛。尽管当前COVID-19大流行的隔离措施可能影响偏头痛负担，但目前尚无关于此问题的信息。目的：在这项研究中，我们的目的是：（1）探索隔离期间偏头痛频率、严重程度和急性药物摄入天数的可能变化;（2）考虑到生活方式的改变、情绪、大流行扩散和COVID-19感染，评估偏头痛结局的可能差异。研究方法：我们采访了纳入观察性意大利头痛登记处（Registro Italiano Cefalee，RICE）的患者，回顾性收集了隔离前（隔离前）和隔离开始后（隔离）2个月内主要头痛特征、生活方式因素、情绪、个体感染状况和对COVID-19的感知的信息。入选标准为：年龄> 18岁，诊断为无先兆偏头痛、有先兆偏头痛和慢性偏头痛，在隔离开始前3个月以上最后一次亲自就诊。结果：共有433名偏头痛患者同意接受采访。我们发现，与隔离前相比，隔离期间头痛频率（9.42 ± 0.43天与8.28 ± 0.41天）和强度（6.57 ± 0.19与6.59 ± 0.21天）总体降低。改善与居家天数之间存在相关性。当结果按地理区域分层时，我们发现北方意大利的头痛频率有恶化的趋势。对病毒感染的厌恶对应于偏头痛的轻微改善。结论：偏头痛患者表现出偏头痛特征的轻度改善，这可能归因于对流行病困扰的弹性行为。对传染病的厌恶，而可能有利于防御行为，可能会使偏头痛恶化。隔离期间偏头痛负担的自发限制有利于通过使用远程医疗访视、可靠的日记和频繁的远程接触对患者进行随访。
Background: Previous studies during SARS and Ebola pandemics have shown that quarantine is associated with several negative psychological effects, such as post-traumatic stress symptoms, confusion, and anger. These conditions may affect the course of many diseases, including migraine. Although it is possible that the quarantine measures for the current COVID-19 pandemic affect migraine burden, no information is currently available on this issue. Aim: In this study, we aimed to: (1) explore the possible changes in migraine frequency, severity, and days with acute medication intake during quarantine period; (2) evaluate possible differences in migraine outcomes in consideration of lifestyle changes, emotions, pandemic diffusion, and COVID-19 infection. Methods: We interviewed patients who were included in the observational Italian Headache Registry (Registro Italiano Cefalee, RICE), retrospectively collecting information on main headache features, lifestyle factors, emotions, individual infection status, and perception of COVID-19 for 2 months before (pre-quarantine) and after the beginning of the quarantine (quarantine). Inclusion criteria were: age > 18, diagnosis of migraine without aura, migraine with aura and chronic migraine, last in-person visit more than 3 months preceding the beginning of quarantine. Results: A total of 433 migraine subjects agreed to be interviewed. We found an overall reduction in headache frequency (9.42 ± 0.43 days with headache vs. 8.28 ± 0.41) and intensity (6.57 ± 0.19 vs. 6.59 ± 0.21) during the quarantine, compared to pre-quarantine. There was a correlation between improvement and number of days of stay-at-home. When results were stratified for geographic area, we found a tendency toward worsening of headache frequency in northern Italy. Disgust regarding viral infection corresponded to a minor improvement in migraine. Conclusions: Migraine patients showed a mild improvement of migraine features, probably attributable to resilient behavior toward pandemic distress. Disgust regarding the contagion whereas potentially favoring defensive behavior, could potentially worsen migraine. The spontaneous limitation of migraine burden during quarantine could favor patient follow-up via the use of telemedicine visits, reliable diaries, and frequent remote contacts.
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影响因子：
11.8
作者：
Hawryluck L;Gold WL;Robinson S;Pogorski S;Galea S;Styra R
通讯作者：
Styra R
DOI：
10.1037/tra0000592
发表时间：
2020-05-01
影响因子：
6.3
作者：
Horesh, Danny;Brown, Adam D.
通讯作者：
Brown, Adam D.
DOI：
10.1007/s42399-020-00348-3
发表时间：
2020-01-01
期刊：
SN comprehensive clinical medicine
影响因子：
--
作者：
Gautam, Mohan;Thakrar, Anjali;Mahr, Greg
通讯作者：
Mahr, Greg
影响因子：
7.4
作者：
Potter, Rachel;Hee, Siew Wan;Matharu, Manjit
通讯作者：
Matharu, Manjit
影响因子：
3.4
作者：
Delussi M;Gentile E;Coppola G;Prudenzano AMP;Rainero I;Sances G;Abagnale C;Caponnetto V;De Cesaris F;Frattale I;Guaschino E;Marcinnò A;Ornello R;Pistoia F;Putortì A;Roca ME;Roveta F;Lupi C;Trojano M;Pierelli F;Geppetti P;Sacco S;de Tommaso M
通讯作者：
de Tommaso M