Interoception as modeling, allostasis as control.

Interoception as modeling, allostasis as control.
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DOI:
10.1016/j.biopsycho.2021.108242
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发表时间:
2022-01
影响因子:
2.6
通讯作者:
Quigley, Karen S.
Quigley, Karen S.
中科院分区:
医学3区
文献类型:
--
作者:
Sennesh, Eli;Theriault, Jordan;Brooks, Dana;van de Meent, Jan-Willem;Barrett, Lisa Feldman;Quigley, Karen S.

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大脑通过预测身体的需求并试图在它们出现之前满足它们来调节身体-这一过程称为变稳态。变稳态需要一个身体内感觉条件变化的模型,这个过程称为内感受。在本文中,我们研究了内感受如何为非稳态提供绩效反馈。我们建议从控制理论的角度来研究变稳态,回顾控制理论在生理学、运动控制和决策等相关问题上的应用。我们合成这些有关它们的重要属性的非稳态调节作为一个控制问题。然后,我们勾勒出一个新的形式主义的大脑可能会执行内脏的变稳态控制类比骨骼运动控制,包括一个数学的观点如何interoception作为性能反馈的变稳态。最后,我们提出了一些方法来测试我们的假设的影响。
The brain regulates the body by anticipating its needs and attempting to meet them before they arise – a process called allostasis. Allostasis requires a model of the changing sensory conditions within the body, a process called interoception. In this paper, we examine how interoception may provide performance feedback for allostasis. We suggest studying allostasis in terms of control theory, reviewing control theory’s applications to related issues in physiology, motor control, and decision making. We synthesize these by relating them to the important properties of allostatic regulation as a control problem. We then sketch a novel formalism for how the brain might perform allostatic control of the viscera by analogy to skeletomotor control, including a mathematical view on how interoception acts as performance feedback for allostasis. Finally, we suggest ways to test implications of our hypotheses.
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